SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010810 FYN ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.975384 View
ENSG00000096717 SIRT1 ENSG00000111424 VDR H. sapiens SSL Slorth 0.975367 View
ENSG00000096717 SIRT1 ENSG00000134086 VHL H. sapiens SSL Slorth 0.975364 View
ENSG00000096717 SIRT1 ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.975305 View
ENSG00000096717 SIRT1 ENSG00000143867 OSR1 H. sapiens SDL Slorth 0.975293 View
ENSG00000096717 SIRT1 ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.975273 View
ENSG00000096717 SIRT1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.975204 View
ENSG00000096717 SIRT1 ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.975117 View
ENSG00000096717 SIRT1 ENSG00000157514 TSC22D3 H. sapiens SDL Slorth 0.975107 View
ENSG00000096717 SIRT1 ENSG00000099804 CDC34 H. sapiens SSL Slorth 0.975062 View
ENSG00000096717 SIRT1 ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.975053 View
ENSG00000096717 SIRT1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.975048 View
ENSG00000096717 SIRT1 ENSG00000116560 SFPQ H. sapiens SSL Slorth 0.975045 View
ENSG00000096717 SIRT1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.975013 View
ENSG00000096717 SIRT1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.975011 View
ENSG00000096717 SIRT1 ENSG00000103197 TSC2 H. sapiens SSL Slorth 0.974995 View
ENSG00000096717 SIRT1 ENSG00000149311 ATM H. sapiens SSL Slorth 0.974911 View
ENSG00000096717 SIRT1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.97489 View
ENSG00000096717 SIRT1 ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.97488 View
ENSG00000096717 SIRT1 ENSG00000130726 TRIM28 H. sapiens SSL Slorth 0.974877 View
ENSG00000096717 SIRT1 ENSG00000175054 ATR H. sapiens SSL Slorth 0.974845 View
ENSG00000096717 SIRT1 ENSG00000116044 NFE2L2 H. sapiens SSL Slorth 0.97484 View
ENSG00000096717 SIRT1 ENSG00000130522 JUND H. sapiens SSL Slorth 0.974839 View
ENSG00000096717 SIRT1 ENSG00000105173 CCNE1 H. sapiens SSL Slorth 0.974828 View
ENSG00000096717 SIRT1 ENSG00000100614 PPM1A H. sapiens SDL Slorth 0.974821 View
ENSG00000096717 SIRT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.97481 View
ENSG00000096717 SIRT1 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.974764 View
ENSG00000096717 SIRT1 ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.974755 View
ENSG00000096717 SIRT1 ENSG00000213341 CHUK H. sapiens SSL Slorth 0.974739 View
ENSG00000096717 SIRT1 ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.974737 View
ENSG00000096717 SIRT1 ENSG00000171223 JUNB H. sapiens SSL Slorth 0.974728 View
ENSG00000096717 SIRT1 ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.974684 View
ENSG00000096717 SIRT1 ENSG00000131747 TOP2A H. sapiens SSL Slorth 0.974569 View
ENSG00000096717 SIRT1 ENSG00000135829 DHX9 H. sapiens SSL Slorth 0.974524 View
ENSG00000096717 SIRT1 ENSG00000099817 POLR2E H. sapiens SSL Slorth 0.974491 View
ENSG00000096717 SIRT1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.974483 View
ENSG00000096717 SIRT1 ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.97447 View
ENSG00000082701 GSK3B ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.974449 View
ENSG00000096717 SIRT1 ENSG00000182208 MOB2 H. sapiens SDL Slorth 0.97442 View
ENSG00000096717 SIRT1 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.974408 View