SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000151532 VTI1A H. sapiens SSL Slorth 0.763315 View
ENSG00000096717 SIRT1 ENSG00000130429 ARPC1B H. sapiens SSL Slorth 0.763206 View
ENSG00000014138 POLA2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.763059 View
ENSG00000096717 SIRT1 ENSG00000102172 SMS H. sapiens SSL Slorth 0.762692 View
ENSG00000096717 SIRT1 ENSG00000114349 GNAT1 H. sapiens SSL Slorth 0.762574 View
ENSG00000096717 SIRT1 ENSG00000169714 CNBP H. sapiens SSL Slorth 0.762552 View
ENSG00000096717 SIRT1 ENSG00000103496 STX4 H. sapiens SSL Slorth 0.76224 View
ENSG00000096717 SIRT1 ENSG00000164171 ITGA2 H. sapiens SSL Slorth 0.762113 View
ENSG00000096717 SIRT1 ENSG00000108590 MED31 H. sapiens SSL Slorth 0.762049 View
ENSG00000096717 SIRT1 ENSG00000143171 RXRG H. sapiens SSL Slorth 0.762046 View
ENSG00000096717 SIRT1 ENSG00000198947 DMD H. sapiens SSL Slorth 0.761875 View
ENSG00000096717 SIRT1 ENSG00000101844 ATG4A H. sapiens SSL Slorth 0.761567 View
ENSG00000096717 SIRT1 ENSG00000204220 PFDN6 H. sapiens SSL Slorth 0.761446 View
ENSG00000090376 IRAK3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.759825 View
ENSG00000096717 SIRT1 ENSG00000116729 WLS H. sapiens SSL Slorth 0.759564 View
ENSG00000096717 SIRT1 ENSG00000170832 USP32 H. sapiens SSL Slorth 0.758973 View
ENSG00000096717 SIRT1 ENSG00000181789 COPG1 H. sapiens SSL Slorth 0.758613 View
ENSG00000096717 SIRT1 ENSG00000129562 DAD1 H. sapiens SSL Slorth 0.758579 View
ENSG00000096717 SIRT1 ENSG00000176105 YES1 H. sapiens SSL Slorth 0.758413 View
ENSG00000096717 SIRT1 ENSG00000124198 ARFGEF2 H. sapiens SSL Slorth 0.75825 View
ENSG00000096717 SIRT1 ENSG00000131165 CHMP1A H. sapiens SSL Slorth 0.758064 View
ENSG00000096717 SIRT1 ENSG00000169230 PRELID1 H. sapiens SSL Slorth 0.757601 View
ENSG00000096717 SIRT1 ENSG00000111348 ARHGDIB H. sapiens SSL Slorth 0.757311 View
ENSG00000096717 SIRT1 ENSG00000100632 ERH H. sapiens SSL Slorth 0.75712 View
ENSG00000096717 SIRT1 ENSG00000156052 GNAQ H. sapiens SSL Slorth 0.756993 View
ENSG00000096717 SIRT1 ENSG00000114573 ATP6V1A H. sapiens SSL Slorth 0.756778 View
ENSG00000054118 THRAP3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.756701 View
ENSG00000096717 SIRT1 ENSG00000100083 GGA1 H. sapiens SSL Slorth 0.756002 View
ENSG00000096717 SIRT1 ENSG00000114302 PRKAR2A H. sapiens SSL Slorth 0.755957 View
ENSG00000074181 NOTCH3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.754863 View
ENSG00000096717 SIRT1 ENSG00000173653 RCE1 H. sapiens SSL Slorth 0.754823 View
ENSG00000096717 SIRT1 ENSG00000184840 TMED9 H. sapiens SSL Slorth 0.754615 View
ENSG00000096717 SIRT1 ENSG00000132842 AP3B1 H. sapiens SSL Slorth 0.75452 View
ENSG00000096717 SIRT1 ENSG00000133101 CCNA1 H. sapiens SSL Slorth 0.754288 View
ENSG00000096717 SIRT1 ENSG00000137710 RDX H. sapiens SSL Slorth 0.754214 View
ENSG00000096717 SIRT1 ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.754172 View
ENSG00000096717 SIRT1 ENSG00000172795 DCP2 H. sapiens SSL Slorth 0.75403 View
ENSG00000092108 SCFD1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.754005 View
ENSG00000096717 SIRT1 ENSG00000198692 EIF1AY H. sapiens SSL Slorth 0.753795 View
ENSG00000096717 SIRT1 ENSG00000103111 MON1B H. sapiens SSL Slorth 0.753676 View