SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000169813 HNRNPF H. sapiens SSL Slorth 0.976665 View
ENSG00000096717 SIRT1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.97658 View
ENSG00000096717 SIRT1 ENSG00000129514 FOXA1 H. sapiens SDL Slorth 0.976544 View
ENSG00000096717 SIRT1 ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.976485 View
ENSG00000096717 SIRT1 ENSG00000101665 SMAD7 H. sapiens SSL Slorth 0.976483 View
ENSG00000096717 SIRT1 ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.976456 View
ENSG00000096717 SIRT1 ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.976445 View
ENSG00000096717 SIRT1 ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.976421 View
ENSG00000096717 SIRT1 ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.976421 View
ENSG00000091831 ESR1 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.976382 View
ENSG00000096717 SIRT1 ENSG00000163132 MSX1 H. sapiens SDL Slorth 0.976326 View
ENSG00000096717 SIRT1 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.976318 View
ENSG00000096717 SIRT1 ENSG00000102054 RBBP7 H. sapiens SSL Slorth 0.976229 View
ENSG00000096717 SIRT1 ENSG00000175832 ETV4 H. sapiens SDL Slorth 0.976128 View
ENSG00000096717 SIRT1 ENSG00000100906 NFKBIA H. sapiens SSL Slorth 0.976081 View
ENSG00000096717 SIRT1 ENSG00000131759 RARA H. sapiens SSL Slorth 0.976022 View
ENSG00000096717 SIRT1 ENSG00000105810 CDK6 H. sapiens SSL Slorth 0.976018 View
ENSG00000096717 SIRT1 ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.975954 View
ENSG00000096717 SIRT1 ENSG00000104852 SNRNP70 H. sapiens SSL Slorth 0.975933 View
ENSG00000096717 SIRT1 ENSG00000119048 UBE2B H. sapiens SSL Slorth 0.975918 View
ENSG00000096717 SIRT1 ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.975884 View
ENSG00000096717 SIRT1 ENSG00000110092 CCND1 H. sapiens SSL Slorth 0.97586 View
ENSG00000096717 SIRT1 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.975845 View
ENSG00000096717 SIRT1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.975837 View
ENSG00000096717 SIRT1 ENSG00000168421 RHOH H. sapiens SDL Slorth 0.97582 View
ENSG00000096717 SIRT1 ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.975793 View
ENSG00000096717 SIRT1 ENSG00000178573 MAF H. sapiens SDL Slorth 0.975788 View
ENSG00000096717 SIRT1 ENSG00000103126 AXIN1 H. sapiens SSL Slorth 0.975719 View
ENSG00000096717 SIRT1 ENSG00000114062 UBE3A H. sapiens SSL Slorth 0.975694 View
ENSG00000096717 SIRT1 ENSG00000145604 SKP2 H. sapiens SSL Slorth 0.975682 View
ENSG00000096717 SIRT1 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.975678 View
ENSG00000096717 SIRT1 ENSG00000108883 EFTUD2 H. sapiens SSL Slorth 0.975677 View
ENSG00000096717 SIRT1 ENSG00000141543 EIF4A3 H. sapiens SSL Slorth 0.97567 View
ENSG00000096717 SIRT1 ENSG00000104738 MCM4 H. sapiens SSL Slorth 0.975556 View
ENSG00000096717 SIRT1 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.975535 View
ENSG00000096717 SIRT1 ENSG00000183765 CHEK2 H. sapiens SSL Slorth 0.975507 View
ENSG00000096717 SIRT1 ENSG00000110777 POU2AF1 H. sapiens SDL Slorth 0.975472 View
ENSG00000096717 SIRT1 ENSG00000105656 ELL H. sapiens SDL Slorth 0.975458 View
ENSG00000096717 SIRT1 ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.975455 View
ENSG00000096717 SIRT1 ENSG00000114166 KAT2B H. sapiens SSL Slorth 0.975385 View