SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000149930 TAOK2 H. sapiens SDL Slorth 0.974311 View
ENSG00000096717 SIRT1 ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.974275 View
ENSG00000096717 SIRT1 ENSG00000159216 RUNX1 H. sapiens SSL Slorth 0.974255 View
ENSG00000096717 SIRT1 ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.974216 View
ENSG00000096717 SIRT1 ENSG00000154447 SH3RF1 H. sapiens SDL Slorth 0.974053 View
ENSG00000096717 SIRT1 ENSG00000166483 WEE1 H. sapiens SSL Slorth 0.974048 View
ENSG00000096717 SIRT1 ENSG00000137486 ARRB1 H. sapiens SSL Slorth 0.974016 View
ENSG00000096717 SIRT1 ENSG00000177889 UBE2N H. sapiens SSL Slorth 0.974016 View
ENSG00000096717 SIRT1 ENSG00000138376 BARD1 H. sapiens SSL Slorth 0.973982 View
ENSG00000096717 SIRT1 ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.973948 View
ENSG00000096717 SIRT1 ENSG00000108443 RPS6KB1 H. sapiens SSL Slorth 0.973938 View
ENSG00000096717 SIRT1 ENSG00000101412 E2F1 H. sapiens SSL Slorth 0.973912 View
ENSG00000096717 SIRT1 ENSG00000132781 MUTYH H. sapiens SDL Slorth 0.973852 View
ENSG00000069869 NEDD4 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.973774 View
ENSG00000096717 SIRT1 ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.973694 View
ENSG00000096717 SIRT1 ENSG00000114503 NCBP2 H. sapiens SSL Slorth 0.973668 View
ENSG00000096717 SIRT1 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.973484 View
ENSG00000096717 SIRT1 ENSG00000135486 HNRNPA1 H. sapiens SSL Slorth 0.973458 View
ENSG00000096717 SIRT1 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.973445 View
ENSG00000096717 SIRT1 ENSG00000101224 CDC25B H. sapiens SSL Slorth 0.973442 View
ENSG00000096717 SIRT1 ENSG00000145632 PLK2 H. sapiens SDL Slorth 0.973406 View
ENSG00000096717 SIRT1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.973333 View
ENSG00000096717 SIRT1 ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.973333 View
ENSG00000096717 SIRT1 ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.973297 View
ENSG00000096717 SIRT1 ENSG00000121774 KHDRBS1 H. sapiens SSL Slorth 0.973295 View
ENSG00000096717 SIRT1 ENSG00000153201 RANBP2 H. sapiens SSL Slorth 0.973246 View
ENSG00000096717 SIRT1 ENSG00000102882 MAPK3 H. sapiens SSL Slorth 0.973217 View
ENSG00000096717 SIRT1 ENSG00000135341 MAP3K7 H. sapiens SSL Slorth 0.973197 View
ENSG00000096717 SIRT1 ENSG00000123080 CDKN2C H. sapiens SDL Slorth 0.973183 View
ENSG00000096717 SIRT1 ENSG00000104881 PPP1R13L H. sapiens SDL Slorth 0.973166 View
ENSG00000096717 SIRT1 ENSG00000132383 RPA1 H. sapiens SSL Slorth 0.973157 View
ENSG00000096717 SIRT1 ENSG00000181449 SOX2 H. sapiens SDL Slorth 0.97315 View
ENSG00000096717 SIRT1 ENSG00000115053 NCL H. sapiens SSL Slorth 0.973145 View
ENSG00000096717 SIRT1 ENSG00000157540 DYRK1A H. sapiens SDL Slorth 0.973128 View
ENSG00000096717 SIRT1 ENSG00000139318 DUSP6 H. sapiens SDL Slorth 0.973066 View
ENSG00000096717 SIRT1 ENSG00000117676 RPS6KA1 H. sapiens SSL Slorth 0.972896 View
ENSG00000096717 SIRT1 ENSG00000103194 USP10 H. sapiens SSL Slorth 0.972885 View
ENSG00000096717 SIRT1 ENSG00000134982 APC H. sapiens SSL Slorth 0.972866 View
ENSG00000096717 SIRT1 ENSG00000113758 DBN1 H. sapiens SDL Slorth 0.972851 View
ENSG00000096717 SIRT1 ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.972774 View