SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000070950 RAD18 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.965996 View
ENSG00000096717 SIRT1 ENSG00000120539 MASTL H. sapiens SDL Slorth 0.965914 View
ENSG00000096717 SIRT1 ENSG00000174738 NR1D2 H. sapiens SDL Slorth 0.965867 View
ENSG00000096717 SIRT1 ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.965803 View
ENSG00000096717 SIRT1 ENSG00000109670 FBXW7 H. sapiens SSL Slorth 0.965786 View
ENSG00000096717 SIRT1 ENSG00000116288 PARK7 H. sapiens SSL Slorth 0.965755 View
ENSG00000085999 RAD54L ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.965751 View
ENSG00000096717 SIRT1 ENSG00000160145 KALRN H. sapiens SDL Slorth 0.965746 View
ENSG00000096717 SIRT1 ENSG00000169967 MAP3K2 H. sapiens SSL Slorth 0.965738 View
ENSG00000096717 SIRT1 ENSG00000105568 PPP2R1A H. sapiens SSL Slorth 0.9657 View
ENSG00000096717 SIRT1 ENSG00000147316 MCPH1 H. sapiens SDL Slorth 0.965683 View
ENSG00000096717 SIRT1 ENSG00000105401 CDC37 H. sapiens SSL Slorth 0.965673 View
ENSG00000087586 AURKA ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.965558 View
ENSG00000096717 SIRT1 ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.965556 View
ENSG00000096717 SIRT1 ENSG00000137055 PLAA H. sapiens SSL Slorth 0.965487 View
ENSG00000096717 SIRT1 ENSG00000102978 POLR2C H. sapiens SSL Slorth 0.965479 View
ENSG00000096717 SIRT1 ENSG00000122566 HNRNPA2B1 H. sapiens SSL Slorth 0.965413 View
ENSG00000096717 SIRT1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.965402 View
ENSG00000096717 SIRT1 ENSG00000137693 YAP1 H. sapiens SSL Slorth 0.96536 View
ENSG00000096717 SIRT1 ENSG00000124782 RREB1 H. sapiens SDL Slorth 0.965289 View
ENSG00000096717 SIRT1 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.965232 View
ENSG00000096717 SIRT1 ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.96518 View
ENSG00000096717 SIRT1 ENSG00000213923 CSNK1E H. sapiens SSL Slorth 0.965179 View
ENSG00000096717 SIRT1 ENSG00000149136 SSRP1 H. sapiens SSL Slorth 0.965097 View
ENSG00000096717 SIRT1 ENSG00000115266 APC2 H. sapiens SDL Slorth 0.965078 View
ENSG00000096717 SIRT1 ENSG00000110107 PRPF19 H. sapiens SSL Slorth 0.965047 View
ENSG00000096717 SIRT1 ENSG00000125870 SNRPB2 H. sapiens SSL Slorth 0.964991 View
ENSG00000005007 UPF1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.964956 View
ENSG00000096717 SIRT1 ENSG00000107807 TLX1 H. sapiens SDL Slorth 0.964911 View
ENSG00000096717 SIRT1 ENSG00000186575 NF2 H. sapiens SSL Slorth 0.964902 View
ENSG00000096717 SIRT1 ENSG00000162924 REL H. sapiens SDL Slorth 0.964871 View
ENSG00000096717 SIRT1 ENSG00000143476 DTL H. sapiens SSL Slorth 0.964863 View
ENSG00000096717 SIRT1 ENSG00000123562 MORF4L2 H. sapiens SSL Slorth 0.96483 View
ENSG00000096717 SIRT1 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.96481 View
ENSG00000063244 U2AF2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.964753 View
ENSG00000096717 SIRT1 ENSG00000165806 CASP7 H. sapiens SSL Slorth 0.964614 View
ENSG00000077092 RARB ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.964515 View
ENSG00000096717 SIRT1 ENSG00000150753 CCT5 H. sapiens SSL Slorth 0.964492 View
ENSG00000096717 SIRT1 ENSG00000185022 MAFF H. sapiens SDL Slorth 0.964375 View
ENSG00000096717 SIRT1 ENSG00000130787 HIP1R H. sapiens SSL Slorth 0.964373 View