SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000160803 UBQLN4 H. sapiens SSL Slorth 0.961238 View
ENSG00000096717 SIRT1 ENSG00000169696 ASPSCR1 H. sapiens SDL Slorth 0.961219 View
ENSG00000096717 SIRT1 ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.96113 View
ENSG00000096717 SIRT1 ENSG00000173039 RELA H. sapiens SSL Slorth 0.961069 View
ENSG00000096717 SIRT1 ENSG00000136573 BLK H. sapiens SDL Slorth 0.96104 View
ENSG00000096717 SIRT1 ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.960927 View
ENSG00000096717 SIRT1 ENSG00000158828 PINK1 H. sapiens SSL Slorth 0.960921 View
ENSG00000096717 SIRT1 ENSG00000121481 RNF2 H. sapiens SSL Slorth 0.960886 View
ENSG00000096717 SIRT1 ENSG00000100201 DDX17 H. sapiens SSL Slorth 0.960877 View
ENSG00000091831 ESR1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.960867 View
ENSG00000096717 SIRT1 ENSG00000178607 ERN1 H. sapiens SSL Slorth 0.960782 View
ENSG00000096717 SIRT1 ENSG00000108424 KPNB1 H. sapiens SSL Slorth 0.960688 View
ENSG00000096717 SIRT1 ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.960638 View
ENSG00000062822 POLD1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.960614 View
ENSG00000096717 SIRT1 ENSG00000124207 CSE1L H. sapiens SSL Slorth 0.960598 View
ENSG00000096717 SIRT1 ENSG00000115317 HTRA2 H. sapiens SDL Slorth 0.960567 View
ENSG00000096717 SIRT1 ENSG00000182511 FES H. sapiens SDL Slorth 0.960475 View
ENSG00000096717 SIRT1 ENSG00000100393 EP300 H. sapiens SDL Slorth 0.960272 View
ENSG00000096717 SIRT1 ENSG00000110713 NUP98 H. sapiens SSL Slorth 0.960266 View
ENSG00000096717 SIRT1 ENSG00000130177 CDC16 H. sapiens SDL Slorth 0.960225 View
ENSG00000096717 SIRT1 ENSG00000100030 MAPK1 H. sapiens SSL Slorth 0.960178 View
ENSG00000096717 SIRT1 ENSG00000163930 BAP1 H. sapiens SSL Slorth 0.960176 View
ENSG00000096717 SIRT1 ENSG00000159259 CHAF1B H. sapiens SSL Slorth 0.960156 View
ENSG00000096717 SIRT1 ENSG00000147162 OGT H. sapiens SDL Slorth 0.960132 View
ENSG00000096717 SIRT1 ENSG00000133316 WDR74 H. sapiens SSL Slorth 0.959994 View
ENSG00000096717 SIRT1 ENSG00000115993 TRAK2 H. sapiens SDL Slorth 0.95996 View
ENSG00000096717 SIRT1 ENSG00000103522 IL21R H. sapiens SDL Slorth 0.959892 View
ENSG00000096717 SIRT1 ENSG00000101349 PAK5 H. sapiens SDL Slorth 0.959869 View
ENSG00000096717 SIRT1 ENSG00000152669 CCNO H. sapiens SDL Slorth 0.959822 View
ENSG00000096717 SIRT1 ENSG00000116017 ARID3A H. sapiens SDL Slorth 0.959798 View
ENSG00000096717 SIRT1 ENSG00000154767 XPC H. sapiens SSL Slorth 0.95975 View
ENSG00000096717 SIRT1 ENSG00000152818 UTRN H. sapiens SDL Slorth 0.95974 View
ENSG00000096717 SIRT1 ENSG00000139613 SMARCC2 H. sapiens SSL Slorth 0.959729 View
ENSG00000096717 SIRT1 ENSG00000135486 HNRNPA1 H. sapiens SDL Slorth 0.959689 View
ENSG00000055332 EIF2AK2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.959678 View
ENSG00000096717 SIRT1 ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.959659 View
ENSG00000096717 SIRT1 ENSG00000168066 SF1 H. sapiens SSL Slorth 0.959633 View
ENSG00000096717 SIRT1 ENSG00000179218 CALR H. sapiens SDL Slorth 0.959625 View
ENSG00000096717 SIRT1 ENSG00000100721 TCL1A H. sapiens SDL Slorth 0.959612 View
ENSG00000096717 SIRT1 ENSG00000134899 ERCC5 H. sapiens SSL Slorth 0.959565 View