ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000105976 MET H. sapiens SDL Slorth 0.991165 View
ENSG00000091831 ESR1 ENSG00000096968 JAK2 H. sapiens SDL Slorth 0.991105 View
ENSG00000091831 ESR1 ENSG00000157873 TNFRSF14 H. sapiens SDL Slorth 0.991052 View
ENSG00000091831 ESR1 ENSG00000164362 TERT H. sapiens SDL Slorth 0.990707 View
ENSG00000091831 ESR1 ENSG00000269858 EGLN2 H. sapiens SDL Slorth 0.990477 View
ENSG00000091831 ESR1 ENSG00000115325 DOK1 H. sapiens SDL Slorth 0.990455 View
ENSG00000091831 ESR1 ENSG00000115232 ITGA4 H. sapiens SDL Slorth 0.990392 View
ENSG00000091831 ESR1 ENSG00000100201 DDX17 H. sapiens SDL Slorth 0.990372 View
ENSG00000091831 ESR1 ENSG00000113712 CSNK1A1 H. sapiens SDL Slorth 0.990172 View
ENSG00000091831 ESR1 ENSG00000177731 FLII H. sapiens SDL Slorth 0.990147 View
ENSG00000091831 ESR1 ENSG00000185950 IRS2 H. sapiens SDL Slorth 0.990025 View
ENSG00000091831 ESR1 ENSG00000179583 CIITA H. sapiens SDL Slorth 0.99002 View
ENSG00000091831 ESR1 ENSG00000183814 LIN9 H. sapiens SDL Slorth 0.989792 View
ENSG00000091831 ESR1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.989676 View
ENSG00000091831 ESR1 ENSG00000131773 KHDRBS3 H. sapiens SDL Slorth 0.989633 View
ENSG00000091831 ESR1 ENSG00000120833 SOCS2 H. sapiens SDL Slorth 0.989516 View
ENSG00000091831 ESR1 ENSG00000178691 SUZ12 H. sapiens SDL Slorth 0.989441 View
ENSG00000091831 ESR1 ENSG00000242173 ARHGDIG H. sapiens SDL Slorth 0.989439 View
ENSG00000091831 ESR1 ENSG00000189079 ARID2 H. sapiens SDL Slorth 0.989378 View
ENSG00000091831 ESR1 ENSG00000118898 PPL H. sapiens SDL Slorth 0.98936 View
ENSG00000091831 ESR1 ENSG00000164050 PLXNB1 H. sapiens SDL Slorth 0.98935 View
ENSG00000091831 ESR1 ENSG00000163513 TGFBR2 H. sapiens SDL Slorth 0.989334 View
ENSG00000091831 ESR1 ENSG00000115904 SOS1 H. sapiens SDL Slorth 0.989279 View
ENSG00000091831 ESR1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.989268 View
ENSG00000091831 ESR1 ENSG00000104825 NFKBIB H. sapiens SDL Slorth 0.989263 View
ENSG00000091831 ESR1 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.989261 View
ENSG00000091831 ESR1 ENSG00000139618 BRCA2 H. sapiens SDL Slorth 0.989259 View
ENSG00000091831 ESR1 ENSG00000105221 AKT2 H. sapiens SDL Slorth 0.98925 View
ENSG00000091831 ESR1 ENSG00000142675 CNKSR1 H. sapiens SDL Slorth 0.989214 View
ENSG00000091831 ESR1 ENSG00000117751 PPP1R8 H. sapiens SDL Slorth 0.989189 View
ENSG00000091831 ESR1 ENSG00000099622 CIRBP H. sapiens SDL Slorth 0.989154 View
ENSG00000091831 ESR1 ENSG00000137764 MAP2K5 H. sapiens SDL Slorth 0.989071 View
ENSG00000091831 ESR1 ENSG00000171105 INSR H. sapiens SDL Slorth 0.989028 View
ENSG00000091831 ESR1 ENSG00000163660 CCNL1 H. sapiens SDL Slorth 0.989003 View
ENSG00000091831 ESR1 ENSG00000175220 ARHGAP1 H. sapiens SDL Slorth 0.989002 View
ENSG00000091831 ESR1 ENSG00000130956 HABP4 H. sapiens SDL Slorth 0.988988 View
ENSG00000091831 ESR1 ENSG00000168148 HIST3H3 H. sapiens SDL Slorth 0.988945 View
ENSG00000091831 ESR1 ENSG00000130382 MLLT1 H. sapiens SDL Slorth 0.988923 View
ENSG00000091831 ESR1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.98889 View
ENSG00000091831 ESR1 ENSG00000134070 IRAK2 H. sapiens SDL Slorth 0.988804 View