ESR1 - TERT

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ESR1	ENSG00000091831	breast	BAZEDOXIFENE DIENESTROL DIETHYLSTILBESTROL DIETHYLSTILBESTROL DIPHOSPHATE ENCLOMIPHENE ESTRADIOL ESTRADIOL ACETATE ESTRADIOL CYPIONATE ESTRADIOL VALERATE ESTROGENS, CONJUGATED ESTROGENS, CONJUGATED SYNTHETIC A ESTROGENS, ESTERIFIED ESTRONE ESTRONE SULFURIC ACID ETHINYL ESTRADIOL FULVESTRANT MESTRANOL OSPEMIFENE POLYESTRADIOL PHOSPHATE QUINESTROL RALOXIFENE SYNTHETIC CONJUGATED ESTROGENS, B TAMOXIFEN TOREMIFENE	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity steroid binding protein binding beta-catenin binding transcription factor binding zinc ion binding enzyme binding nitric-oxide synthase regulator activity estrogen receptor activity estrogen response element binding RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding identical protein binding ATPase binding	No GO terms in record
TERT	ENSG00000164362	melanoma glioblastoma hepatocellular carcinoma bladder skin basal cell skin squamous cell mesothelioma medulloblastoma other tumour types	No drugs in record	tRNA binding transcription coactivator binding DNA binding telomerase activity telomerase RNA reverse transcriptase activity RNA binding RNA-directed DNA polymerase activity protein binding nucleotidyltransferase activity telomeric DNA binding protein homodimerization activity metal ion binding telomerase RNA binding RNA-directed 5'-3' RNA polymerase activity	EST2 (S. cerevisiae)