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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
All
Experimentally Validated
Cancer:
Cancer gene:
Drug search:
Druggable:
Pathway:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
CHEK1
ENSG00000149554
H. sapiens
protein kinase activity
protein serine/threonine kinase activity
protein binding
...
2535
ADA
ENSG00000196839
H. sapiens
DIPYRIDAMOLE
PENTOSTATIN
purine nucleoside binding
adenosine deaminase activity
protein binding
...
201
BRCA1
ENSG00000012048
H. sapiens
ovarian
breast
DNA binding
damaged DNA binding
transcription coactivator activity
...
4860
BRCA2
ENSG00000139618
H. sapiens
breast
ovarian
pancreatic
leukaemia
protease binding
single-stranded DNA binding
protein binding
...
340
C10orf76
ENSG00000120029
H. sapiens
protein binding
...
15
GOSR1
ENSG00000108587
H. sapiens
SNARE binding
SNAP receptor activity
...
250
KRAS
ENSG00000133703
H. sapiens
pancreatic
colorectal
lung
thyroid
AML
other tumour types
GTPase activity
protein binding
GTP binding
...
3905
PTAR1
ENSG00000188647
H. sapiens
protein prenyltransferase activity
...
60
RAB1A
ENSG00000138069
H. sapiens
GTPase activity
protein binding
GTP binding
...
3143
A2M
ENSG00000175899
H. sapiens
protease binding
serine-type endopeptidase inhibitor activity
GTPase activator activity
...
71
AANAT
ENSG00000129673
H. sapiens
aralkylamine N-acetyltransferase activity
arylamine N-acetyltransferase activity
protein binding
...
3
AARS2
ENSG00000124608
H. sapiens
tRNA binding
alanine-tRNA ligase activity
ATP binding
...
1
AATF
ENSG00000276072
H. sapiens
transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
...
3
ABCB5
ENSG00000004846
H. sapiens
ATP binding
xenobiotic-transporting ATPase activity
efflux transmembrane transporter activity
...
1
ABCB7
ENSG00000131269
H. sapiens
ATP binding
heme transporter activity
ATPase activity, coupled to transmembrane movement of substances
...
8
ABL1
ENSG00000097007
H. sapiens
CML
ALL
T-ALL
BOSUTINIB
DASATINIB
IMATINIB
NILOTINIB
PONATINIB
PONATINIB
REGORAFENIB
magnesium ion binding
DNA binding
actin monomer binding
...
3934
ACSM4
ENSG00000215009
H. sapiens
acyl-CoA ligase activity
fatty-acyl-CoA synthase activity
ATP binding
...
1
ACTL6A
ENSG00000136518
H. sapiens
chromatin binding
transcription coactivator activity
protein binding
...
965
ACTR10
ENSG00000131966
H. sapiens
protein binding
...
15
ACTR2
ENSG00000138071
H. sapiens
structural constituent of cytoskeleton
ATP binding
actin filament binding
...
321
ACTR5
ENSG00000101442
H. sapiens
protein binding
...
153
ACTR8
ENSG00000113812
H. sapiens
protein binding
ATP binding
...
158
ACVR1
ENSG00000115170
H. sapiens
DIPG
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
...
61
ACVRL1
ENSG00000139567
H. sapiens
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
...
153
ACY1
ENSG00000243989
H. sapiens
aminoacylase activity
protein binding
zinc ion binding
...
2
ADAM22
ENSG00000008277
H. sapiens
metalloendopeptidase activity
integrin binding
protein binding
...
8
ADAMTSL5
ENSG00000185761
H. sapiens
metalloendopeptidase activity
heparin binding
zinc ion binding
...
1
ADAT2
ENSG00000189007
H. sapiens
protein binding
zinc ion binding
tRNA-specific adenosine-34 deaminase activity
...
2
ADCY8
ENSG00000155897
H. sapiens
adenylate cyclase activity
ATP binding
calcium- and calmodulin-responsive adenylate cyclase activity
...
17
ADPRM
ENSG00000170222
H. sapiens
metal ion binding
ADP-ribose diphosphatase activity
CDP-glycerol diphosphatase activity
...
2
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