ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000261796 ISY1-RAB43 H. sapiens SSL Slorth 0.766656 View
ENSG00000091831 ESR1 ENSG00000117133 RPF1 H. sapiens SSL Slorth 0.766279 View
ENSG00000091831 ESR1 ENSG00000178741 COX5A H. sapiens SSL Slorth 0.766141 View
ENSG00000091831 ESR1 ENSG00000106636 YKT6 H. sapiens SSL Slorth 0.765855 View
ENSG00000091831 ESR1 ENSG00000197114 ZGPAT H. sapiens SSL Slorth 0.765668 View
ENSG00000091831 ESR1 ENSG00000100485 SOS2 H. sapiens SSL Slorth 0.765659 View
ENSG00000091831 ESR1 ENSG00000104643 MTMR9 H. sapiens SSL Slorth 0.765398 View
ENSG00000091831 ESR1 ENSG00000182149 IST1 H. sapiens SSL Slorth 0.765292 View
ENSG00000091831 ESR1 ENSG00000101144 BMP7 H. sapiens SSL Slorth 0.765112 View
ENSG00000091831 ESR1 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.764726 View
ENSG00000091831 ESR1 ENSG00000125378 BMP4 H. sapiens SSL Slorth 0.764673 View
ENSG00000091831 ESR1 ENSG00000128829 EIF2AK4 H. sapiens SSL Slorth 0.764229 View
ENSG00000091831 ESR1 ENSG00000175634 RPS6KB2 H. sapiens SSL Slorth 0.764189 View
ENSG00000091831 ESR1 ENSG00000141380 SS18 H. sapiens SSL Slorth 0.763761 View
ENSG00000091831 ESR1 ENSG00000145782 ATG12 H. sapiens SSL Slorth 0.763498 View
ENSG00000091831 ESR1 ENSG00000196611 MMP1 H. sapiens SSL Slorth 0.763308 View
ENSG00000091831 ESR1 ENSG00000111252 SH2B3 H. sapiens SSL Slorth 0.762745 View
ENSG00000091831 ESR1 ENSG00000213672 NCKIPSD H. sapiens SSL Slorth 0.76273 View
ENSG00000091831 ESR1 ENSG00000151148 UBE3B H. sapiens SSL Slorth 0.762647 View
ENSG00000091831 ESR1 ENSG00000113140 SPARC H. sapiens SSL Slorth 0.762527 View
ENSG00000006451 RALA ENSG00000091831 ESR1 H. sapiens SSL Slorth 0.762008 View
ENSG00000091831 ESR1 ENSG00000133101 CCNA1 H. sapiens SSL Slorth 0.761546 View
ENSG00000091831 ESR1 ENSG00000179091 CYC1 H. sapiens SSL Slorth 0.761319 View
ENSG00000091831 ESR1 ENSG00000198830 HMGN2 H. sapiens SSL Slorth 0.760605 View
ENSG00000091831 ESR1 ENSG00000122882 ECD H. sapiens SSL Slorth 0.760422 View
ENSG00000091831 ESR1 ENSG00000198380 GFPT1 H. sapiens SSL Slorth 0.759824 View
ENSG00000091831 ESR1 ENSG00000136758 YME1L1 H. sapiens SSL Slorth 0.758745 View
ENSG00000091831 ESR1 ENSG00000105220 GPI H. sapiens SSL Slorth 0.758669 View
ENSG00000091831 ESR1 ENSG00000266173 STRADA H. sapiens SSL Slorth 0.758374 View
ENSG00000091831 ESR1 ENSG00000240344 PPIL3 H. sapiens SSL Slorth 0.758259 View
ENSG00000091831 ESR1 ENSG00000135047 CTSL H. sapiens SSL Slorth 0.757179 View
ENSG00000091831 ESR1 ENSG00000185615 PDIA2 H. sapiens SSL Slorth 0.756836 View
ENSG00000091831 ESR1 ENSG00000128578 STRIP2 H. sapiens SSL Slorth 0.756728 View
ENSG00000091831 ESR1 ENSG00000198467 TPM2 H. sapiens SSL Slorth 0.756448 View
ENSG00000091831 ESR1 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.75616 View
ENSG00000091831 ESR1 ENSG00000132849 PATJ H. sapiens SSL Slorth 0.755908 View
ENSG00000091831 ESR1 ENSG00000127337 YEATS4 H. sapiens SSL Slorth 0.75574 View
ENSG00000091831 ESR1 ENSG00000132912 DCTN4 H. sapiens SSL Slorth 0.755678 View
ENSG00000091831 ESR1 ENSG00000168092 PAFAH1B2 H. sapiens SSL Slorth 0.755613 View
ENSG00000091831 ESR1 ENSG00000162775 RBM15 H. sapiens SSL Slorth 0.755527 View