ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000107796 ACTA2 H. sapiens SSL Slorth 0.8105 View
ENSG00000091831 ESR1 ENSG00000117859 OSBPL9 H. sapiens SSL Slorth 0.810472 View
ENSG00000091831 ESR1 ENSG00000124145 SDC4 H. sapiens SSL Slorth 0.810452 View
ENSG00000091831 ESR1 ENSG00000153234 NR4A2 H. sapiens SSL Slorth 0.810314 View
ENSG00000070010 UFD1L ENSG00000091831 ESR1 H. sapiens SSL Slorth 0.810262 View
ENSG00000091831 ESR1 ENSG00000173273 TNKS H. sapiens SSL Slorth 0.810235 View
ENSG00000091831 ESR1 ENSG00000108039 XPNPEP1 H. sapiens SSL Slorth 0.810223 View
ENSG00000091831 ESR1 ENSG00000178921 PFAS H. sapiens SSL Slorth 0.810188 View
ENSG00000091831 ESR1 ENSG00000177169 ULK1 H. sapiens SSL Slorth 0.809999 View
ENSG00000091831 ESR1 ENSG00000204120 GIGYF2 H. sapiens SSL Slorth 0.80986 View
ENSG00000091831 ESR1 ENSG00000135069 PSAT1 H. sapiens SSL Slorth 0.809768 View
ENSG00000091831 ESR1 ENSG00000112062 MAPK14 H. sapiens SSL Slorth 0.809566 View
ENSG00000091831 ESR1 ENSG00000187239 FNBP1 H. sapiens SSL Slorth 0.8094 View
ENSG00000091831 ESR1 ENSG00000110880 CORO1C H. sapiens SSL Slorth 0.809376 View
ENSG00000091831 ESR1 ENSG00000211456 SACM1L H. sapiens SSL Slorth 0.809306 View
ENSG00000091831 ESR1 ENSG00000108010 GLRX3 H. sapiens SSL Slorth 0.809306 View
ENSG00000091831 ESR1 ENSG00000133216 EPHB2 H. sapiens SSL Slorth 0.808981 View
ENSG00000091831 ESR1 ENSG00000176986 SEC24C H. sapiens SSL Slorth 0.808784 View
ENSG00000091831 ESR1 ENSG00000164050 PLXNB1 H. sapiens SSL Slorth 0.808724 View
ENSG00000091831 ESR1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.808565 View
ENSG00000091831 ESR1 ENSG00000131236 CAP1 H. sapiens SSL Slorth 0.808533 View
ENSG00000091831 ESR1 ENSG00000185386 MAPK11 H. sapiens SSL Slorth 0.808076 View
ENSG00000091831 ESR1 ENSG00000186184 POLR1D H. sapiens SSL Slorth 0.808063 View
ENSG00000091831 ESR1 ENSG00000116731 PRDM2 H. sapiens SSL Slorth 0.807659 View
ENSG00000091831 ESR1 ENSG00000137040 RANBP6 H. sapiens SSL Slorth 0.80764 View
ENSG00000091831 ESR1 ENSG00000109458 GAB1 H. sapiens SSL Slorth 0.807005 View
ENSG00000091831 ESR1 ENSG00000131381 RBSN H. sapiens SSL Slorth 0.806954 View
ENSG00000091831 ESR1 ENSG00000160208 RRP1B H. sapiens SSL Slorth 0.806877 View
ENSG00000091831 ESR1 ENSG00000128626 MRPS12 H. sapiens SSL Slorth 0.80669 View
ENSG00000091831 ESR1 ENSG00000204389 HSPA1A H. sapiens SSL Slorth 0.806605 View
ENSG00000091831 ESR1 ENSG00000196576 PLXNB2 H. sapiens SSL Slorth 0.806451 View
ENSG00000091831 ESR1 ENSG00000167323 STIM1 H. sapiens SSL Slorth 0.806323 View
ENSG00000091831 ESR1 ENSG00000129170 CSRP3 H. sapiens SSL Slorth 0.806277 View
ENSG00000091831 ESR1 ENSG00000140307 GTF2A2 H. sapiens SSL Slorth 0.806227 View
ENSG00000091831 ESR1 ENSG00000101265 RASSF2 H. sapiens SSL Slorth 0.805974 View
ENSG00000091831 ESR1 ENSG00000173626 TRAPPC3L H. sapiens SSL Slorth 0.80592 View
ENSG00000091831 ESR1 ENSG00000100721 TCL1A H. sapiens SSL Slorth 0.805807 View
ENSG00000091831 ESR1 ENSG00000105438 KDELR1 H. sapiens SSL Slorth 0.805687 View
ENSG00000091831 ESR1 ENSG00000106355 LSM5 H. sapiens SSL Slorth 0.805625 View
ENSG00000091831 ESR1 ENSG00000197905 TEAD4 H. sapiens SSL Slorth 0.805531 View