ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000153071 DAB2 H. sapiens SDL Slorth 0.988756 View
ENSG00000091831 ESR1 ENSG00000173846 PLK3 H. sapiens SDL Slorth 0.988652 View
ENSG00000091831 ESR1 ENSG00000146535 GNA12 H. sapiens SDL Slorth 0.988573 View
ENSG00000091831 ESR1 ENSG00000173801 JUP H. sapiens SDL Slorth 0.988569 View
ENSG00000091831 ESR1 ENSG00000106803 SEC61B H. sapiens SDL Slorth 0.988557 View
ENSG00000091831 ESR1 ENSG00000198001 IRAK4 H. sapiens SDL Slorth 0.988527 View
ENSG00000091831 ESR1 ENSG00000130037 KCNA5 H. sapiens SDL Slorth 0.988493 View
ENSG00000091831 ESR1 ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.988373 View
ENSG00000091831 ESR1 ENSG00000157514 TSC22D3 H. sapiens SDL Slorth 0.988319 View
ENSG00000091831 ESR1 ENSG00000092969 TGFB2 H. sapiens SDL Slorth 0.988291 View
ENSG00000091831 ESR1 ENSG00000099875 MKNK2 H. sapiens SDL Slorth 0.98829 View
ENSG00000091831 ESR1 ENSG00000154380 ENAH H. sapiens SDL Slorth 0.988266 View
ENSG00000091831 ESR1 ENSG00000139220 PPFIA2 H. sapiens SDL Slorth 0.988237 View
ENSG00000091831 ESR1 ENSG00000177189 RPS6KA3 H. sapiens SDL Slorth 0.988226 View
ENSG00000091831 ESR1 ENSG00000109339 MAPK10 H. sapiens SDL Slorth 0.988092 View
ENSG00000091831 ESR1 ENSG00000112701 SENP6 H. sapiens SDL Slorth 0.988028 View
ENSG00000091831 ESR1 ENSG00000117020 AKT3 H. sapiens SDL Slorth 0.988026 View
ENSG00000091831 ESR1 ENSG00000126214 KLC1 H. sapiens SDL Slorth 0.98802 View
ENSG00000091831 ESR1 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.988011 View
ENSG00000091831 ESR1 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.988011 View
ENSG00000091831 ESR1 ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.988011 View
ENSG00000091831 ESR1 ENSG00000136492 BRIP1 H. sapiens SDL Slorth 0.987983 View
ENSG00000091831 ESR1 ENSG00000140807 NKD1 H. sapiens SDL Slorth 0.987975 View
ENSG00000091831 ESR1 ENSG00000105647 PIK3R2 H. sapiens SDL Slorth 0.987938 View
ENSG00000091831 ESR1 ENSG00000169252 ADRB2 H. sapiens SDL Slorth 0.987914 View
ENSG00000091831 ESR1 ENSG00000140538 NTRK3 H. sapiens SDL Slorth 0.987889 View
ENSG00000091831 ESR1 ENSG00000198561 CTNND1 H. sapiens SDL Slorth 0.987861 View
ENSG00000091831 ESR1 ENSG00000106546 AHR H. sapiens SDL Slorth 0.987791 View
ENSG00000091831 ESR1 ENSG00000124216 SNAI1 H. sapiens SDL Slorth 0.98771 View
ENSG00000091831 ESR1 ENSG00000175354 PTPN2 H. sapiens SDL Slorth 0.987703 View
ENSG00000091831 ESR1 ENSG00000130402 ACTN4 H. sapiens SDL Slorth 0.987684 View
ENSG00000091831 ESR1 ENSG00000136754 ABI1 H. sapiens SDL Slorth 0.98768 View
ENSG00000091831 ESR1 ENSG00000140575 IQGAP1 H. sapiens SDL Slorth 0.987653 View
ENSG00000091831 ESR1 ENSG00000159593 NAE1 H. sapiens SDL Slorth 0.987645 View
ENSG00000091831 ESR1 ENSG00000117713 ARID1A H. sapiens SDL Slorth 0.98764 View
ENSG00000091831 ESR1 ENSG00000150995 ITPR1 H. sapiens SDL Slorth 0.987606 View
ENSG00000091831 ESR1 ENSG00000117676 RPS6KA1 H. sapiens SDL Slorth 0.987538 View
ENSG00000091831 ESR1 ENSG00000160293 VAV2 H. sapiens SDL Slorth 0.987508 View
ENSG00000091831 ESR1 ENSG00000163629 PTPN13 H. sapiens SDL Slorth 0.987499 View
ENSG00000091831 ESR1 ENSG00000160271 RALGDS H. sapiens SDL Slorth 0.987454 View