ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000105063 PPP6R1 H. sapiens SDL Slorth 0.984863 View
ENSG00000091831 ESR1 ENSG00000134323 MYCN H. sapiens SDL Slorth 0.984862 View
ENSG00000091831 ESR1 ENSG00000111450 STX2 H. sapiens SDL Slorth 0.984862 View
ENSG00000091831 ESR1 ENSG00000155846 PPARGC1B H. sapiens SDL Slorth 0.984843 View
ENSG00000091831 ESR1 ENSG00000136574 GATA4 H. sapiens SDL Slorth 0.98482 View
ENSG00000086619 ERO1B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984818 View
ENSG00000088367 EPB41L1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984809 View
ENSG00000091831 ESR1 ENSG00000131408 NR1H2 H. sapiens SDL Slorth 0.984805 View
ENSG00000091831 ESR1 ENSG00000134480 CCNH H. sapiens SDL Slorth 0.984755 View
ENSG00000091831 ESR1 ENSG00000168453 HR H. sapiens SDL Slorth 0.984732 View
ENSG00000091831 ESR1 ENSG00000131475 VPS25 H. sapiens SDL Slorth 0.984715 View
ENSG00000091831 ESR1 ENSG00000135144 DTX1 H. sapiens SDL Slorth 0.98471 View
ENSG00000091831 ESR1 ENSG00000151422 FER H. sapiens SDL Slorth 0.984703 View
ENSG00000091831 ESR1 ENSG00000143476 DTL H. sapiens SDL Slorth 0.984702 View
ENSG00000079156 OSBPL6 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984688 View
ENSG00000077380 DYNC1I2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984688 View
ENSG00000091831 ESR1 ENSG00000140022 STON2 H. sapiens SDL Slorth 0.984687 View
ENSG00000091831 ESR1 ENSG00000112242 E2F3 H. sapiens SDL Slorth 0.984643 View
ENSG00000091831 ESR1 ENSG00000187323 DCC H. sapiens SDL Slorth 0.984607 View
ENSG00000091831 ESR1 ENSG00000132326 PER2 H. sapiens SDL Slorth 0.984606 View
ENSG00000091831 ESR1 ENSG00000245848 CEBPA H. sapiens SDL Slorth 0.984582 View
ENSG00000091831 ESR1 ENSG00000114030 KPNA1 H. sapiens SDL Slorth 0.984567 View
ENSG00000091831 ESR1 ENSG00000175592 FOSL1 H. sapiens SDL Slorth 0.984551 View
ENSG00000091831 ESR1 ENSG00000102054 RBBP7 H. sapiens SDL Slorth 0.98451 View
ENSG00000091831 ESR1 ENSG00000205339 IPO7 H. sapiens SDL Slorth 0.984456 View
ENSG00000091831 ESR1 ENSG00000113916 BCL6 H. sapiens SDL Slorth 0.984455 View
ENSG00000076928 ARHGEF1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984448 View
ENSG00000091831 ESR1 ENSG00000169554 ZEB2 H. sapiens SDL Slorth 0.984445 View
ENSG00000091831 ESR1 ENSG00000115738 ID2 H. sapiens SDL Slorth 0.984444 View
ENSG00000079335 CDC14A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984439 View
ENSG00000091831 ESR1 ENSG00000160255 ITGB2 H. sapiens SDL Slorth 0.984436 View
ENSG00000091831 ESR1 ENSG00000138696 BMPR1B H. sapiens SDL Slorth 0.984433 View
ENSG00000091831 ESR1 ENSG00000168078 PBK H. sapiens SDL Slorth 0.984406 View
ENSG00000091831 ESR1 ENSG00000141985 SH3GL1 H. sapiens SDL Slorth 0.984342 View
ENSG00000091831 ESR1 ENSG00000123405 NFE2 H. sapiens SDL Slorth 0.984324 View
ENSG00000085449 WDFY1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984304 View
ENSG00000091831 ESR1 ENSG00000143258 USP21 H. sapiens SDL Slorth 0.98428 View
ENSG00000091831 ESR1 ENSG00000173334 TRIB1 H. sapiens SDL Slorth 0.984272 View
ENSG00000091831 ESR1 ENSG00000171223 JUNB H. sapiens SDL Slorth 0.98425 View
ENSG00000091831 ESR1 ENSG00000171608 PIK3CD H. sapiens SDL Slorth 0.984222 View