ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000178209 PLEC H. sapiens SDL Slorth 0.986531 View
ENSG00000091831 ESR1 ENSG00000162302 RPS6KA4 H. sapiens SDL Slorth 0.986504 View
ENSG00000091831 ESR1 ENSG00000164867 NOS3 H. sapiens SDL Slorth 0.986497 View
ENSG00000091831 ESR1 ENSG00000108984 MAP2K6 H. sapiens SDL Slorth 0.986441 View
ENSG00000091831 ESR1 ENSG00000121966 CXCR4 H. sapiens SDL Slorth 0.986428 View
ENSG00000091831 ESR1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.986354 View
ENSG00000091831 ESR1 ENSG00000119535 CSF3R H. sapiens SDL Slorth 0.986322 View
ENSG00000091831 ESR1 ENSG00000198648 STK39 H. sapiens SDL Slorth 0.986289 View
ENSG00000091831 ESR1 ENSG00000147443 DOK2 H. sapiens SDL Slorth 0.986287 View
ENSG00000091831 ESR1 ENSG00000107036 RIC1 H. sapiens SDL Slorth 0.986287 View
ENSG00000091831 ESR1 ENSG00000143322 ABL2 H. sapiens SDL Slorth 0.986266 View
ENSG00000091831 ESR1 ENSG00000104964 AES H. sapiens SDL Slorth 0.986246 View
ENSG00000091831 ESR1 ENSG00000154310 TNIK H. sapiens SDL Slorth 0.986244 View
ENSG00000091831 ESR1 ENSG00000129993 CBFA2T3 H. sapiens SDL Slorth 0.98623 View
ENSG00000091831 ESR1 ENSG00000106993 CDC37L1 H. sapiens SDL Slorth 0.986226 View
ENSG00000091831 ESR1 ENSG00000181929 PRKAG1 H. sapiens SDL Slorth 0.986192 View
ENSG00000091831 ESR1 ENSG00000169891 REPS2 H. sapiens SDL Slorth 0.986184 View
ENSG00000091831 ESR1 ENSG00000130522 JUND H. sapiens SDL Slorth 0.986181 View
ENSG00000091831 ESR1 ENSG00000198719 DLL1 H. sapiens SDL Slorth 0.986156 View
ENSG00000091831 ESR1 ENSG00000166477 LEO1 H. sapiens SDL Slorth 0.986143 View
ENSG00000091831 ESR1 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.986056 View
ENSG00000091831 ESR1 ENSG00000187098 MITF H. sapiens SDL Slorth 0.986052 View
ENSG00000091831 ESR1 ENSG00000135424 ITGA7 H. sapiens SDL Slorth 0.985966 View
ENSG00000091831 ESR1 ENSG00000126883 NUP214 H. sapiens SDL Slorth 0.985937 View
ENSG00000091831 ESR1 ENSG00000134215 VAV3 H. sapiens SDL Slorth 0.985919 View
ENSG00000091831 ESR1 ENSG00000105245 NUMBL H. sapiens SDL Slorth 0.985889 View
ENSG00000091831 ESR1 ENSG00000116604 MEF2D H. sapiens SDL Slorth 0.985847 View
ENSG00000091831 ESR1 ENSG00000105810 CDK6 H. sapiens SDL Slorth 0.985838 View
ENSG00000091831 ESR1 ENSG00000113360 DROSHA H. sapiens SDL Slorth 0.985819 View
ENSG00000091831 ESR1 ENSG00000140299 BNIP2 H. sapiens SDL Slorth 0.985804 View
ENSG00000091831 ESR1 ENSG00000112576 CCND3 H. sapiens SDL Slorth 0.985788 View
ENSG00000023318 ERP44 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.985773 View
ENSG00000091831 ESR1 ENSG00000125107 CNOT1 H. sapiens SDL Slorth 0.985769 View
ENSG00000091831 ESR1 ENSG00000169750 RAC3 H. sapiens SDL Slorth 0.985755 View
ENSG00000091831 ESR1 ENSG00000125378 BMP4 H. sapiens SDL Slorth 0.985748 View
ENSG00000091831 ESR1 ENSG00000154001 PPP2R5E H. sapiens SDL Slorth 0.985735 View
ENSG00000091831 ESR1 ENSG00000158169 FANCC H. sapiens SDL Slorth 0.98573 View
ENSG00000091831 ESR1 ENSG00000133112 TPT1 H. sapiens SDL Slorth 0.985723 View
ENSG00000073350 LLGL2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.98571 View
ENSG00000091831 ESR1 ENSG00000155511 GRIA1 H. sapiens SDL Slorth 0.985701 View