ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000138032 PPM1B H. sapiens SDL Slorth 0.984222 View
ENSG00000091831 ESR1 ENSG00000106571 GLI3 H. sapiens SDL Slorth 0.98422 View
ENSG00000091831 ESR1 ENSG00000152795 HNRNPDL H. sapiens SDL Slorth 0.984218 View
ENSG00000091831 ESR1 ENSG00000175832 ETV4 H. sapiens SDL Slorth 0.984209 View
ENSG00000091831 ESR1 ENSG00000168646 AXIN2 H. sapiens SDL Slorth 0.984202 View
ENSG00000091831 ESR1 ENSG00000134371 CDC73 H. sapiens SDL Slorth 0.984179 View
ENSG00000091831 ESR1 ENSG00000106799 TGFBR1 H. sapiens SDL Slorth 0.984171 View
ENSG00000091831 ESR1 ENSG00000100307 CBX7 H. sapiens SDL Slorth 0.984164 View
ENSG00000086827 ZW10 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.98416 View
ENSG00000091831 ESR1 ENSG00000109819 PPARGC1A H. sapiens SDL Slorth 0.984135 View
ENSG00000091831 ESR1 ENSG00000172175 MALT1 H. sapiens SDL Slorth 0.984119 View
ENSG00000091831 ESR1 ENSG00000167004 PDIA3 H. sapiens SDL Slorth 0.984112 View
ENSG00000091831 ESR1 ENSG00000186298 PPP1CC H. sapiens SDL Slorth 0.984105 View
ENSG00000072163 LIMS2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.984092 View
ENSG00000091831 ESR1 ENSG00000106070 GRB10 H. sapiens SDL Slorth 0.984028 View
ENSG00000091831 ESR1 ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.984006 View
ENSG00000091831 ESR1 ENSG00000092529 CAPN3 H. sapiens SDL Slorth 0.983993 View
ENSG00000057608 GDI2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983977 View
ENSG00000091831 ESR1 ENSG00000173473 SMARCC1 H. sapiens SDL Slorth 0.983963 View
ENSG00000091831 ESR1 ENSG00000116731 PRDM2 H. sapiens SDL Slorth 0.983933 View
ENSG00000091831 ESR1 ENSG00000142273 CBLC H. sapiens SDL Slorth 0.98393 View
ENSG00000091831 ESR1 ENSG00000175745 NR2F1 H. sapiens SDL Slorth 0.983919 View
ENSG00000091831 ESR1 ENSG00000144554 FANCD2 H. sapiens SDL Slorth 0.983898 View
ENSG00000077279 DCX ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983891 View
ENSG00000091831 ESR1 ENSG00000221823 PPP3R1 H. sapiens SDL Slorth 0.983889 View
ENSG00000091831 ESR1 ENSG00000221829 FANCG H. sapiens SDL Slorth 0.983873 View
ENSG00000091831 ESR1 ENSG00000115310 RTN4 H. sapiens SDL Slorth 0.983863 View
ENSG00000091831 ESR1 ENSG00000197323 TRIM33 H. sapiens SDL Slorth 0.983841 View
ENSG00000091831 ESR1 ENSG00000144381 HSPD1 H. sapiens SDL Slorth 0.983786 View
ENSG00000091831 ESR1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.983768 View
ENSG00000085999 RAD54L ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983745 View
ENSG00000091831 ESR1 ENSG00000156709 AIFM1 H. sapiens SDL Slorth 0.983744 View
ENSG00000091831 ESR1 ENSG00000110422 HIPK3 H. sapiens SDL Slorth 0.983743 View
ENSG00000091831 ESR1 ENSG00000166851 PLK1 H. sapiens SDL Slorth 0.983732 View
ENSG00000091831 ESR1 ENSG00000131263 RLIM H. sapiens SDL Slorth 0.983731 View
ENSG00000091831 ESR1 ENSG00000133703 KRAS H. sapiens SDL Slorth 0.983724 View
ENSG00000091831 ESR1 ENSG00000100401 RANGAP1 H. sapiens SDL Slorth 0.983719 View
ENSG00000091831 ESR1 ENSG00000108604 SMARCD2 H. sapiens SDL Slorth 0.983712 View
ENSG00000076067 RBMS2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983709 View
ENSG00000091831 ESR1 ENSG00000165732 DDX21 H. sapiens SDL Slorth 0.983671 View