ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000187741 FANCA H. sapiens SDL Slorth 0.982964 View
ENSG00000091831 ESR1 ENSG00000112237 CCNC H. sapiens SDL Slorth 0.982951 View
ENSG00000066027 PPP2R5A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982949 View
ENSG00000091831 ESR1 ENSG00000127445 PIN1 H. sapiens SDL Slorth 0.982908 View
ENSG00000091831 ESR1 ENSG00000187239 FNBP1 H. sapiens SDL Slorth 0.982905 View
ENSG00000091831 ESR1 ENSG00000143801 PSEN2 H. sapiens SDL Slorth 0.982903 View
ENSG00000091831 ESR1 ENSG00000129315 CCNT1 H. sapiens SDL Slorth 0.982878 View
ENSG00000091831 ESR1 ENSG00000150459 SAP18 H. sapiens SDL Slorth 0.982855 View
ENSG00000091831 ESR1 ENSG00000102974 CTCF H. sapiens SDL Slorth 0.982804 View
ENSG00000091831 ESR1 ENSG00000136450 SRSF1 H. sapiens SDL Slorth 0.982785 View
ENSG00000091831 ESR1 ENSG00000152484 USP12 H. sapiens SDL Slorth 0.982764 View
ENSG00000070718 AP3M2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982717 View
ENSG00000066923 STAG3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982709 View
ENSG00000091831 ESR1 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.982707 View
ENSG00000064933 PMS1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982684 View
ENSG00000091831 ESR1 ENSG00000175197 DDIT3 H. sapiens SDL Slorth 0.982668 View
ENSG00000091831 ESR1 ENSG00000162733 DDR2 H. sapiens SDL Slorth 0.982651 View
ENSG00000091831 ESR1 ENSG00000185811 IKZF1 H. sapiens SDL Slorth 0.982646 View
ENSG00000091831 ESR1 ENSG00000100888 CHD8 H. sapiens SDL Slorth 0.982642 View
ENSG00000091831 ESR1 ENSG00000123124 WWP1 H. sapiens SDL Slorth 0.982639 View
ENSG00000091831 ESR1 ENSG00000163161 ERCC3 H. sapiens SDL Slorth 0.982618 View
ENSG00000091831 ESR1 ENSG00000165416 SUGT1 H. sapiens SDL Slorth 0.982617 View
ENSG00000091831 ESR1 ENSG00000161638 ITGA5 H. sapiens SDL Slorth 0.982611 View
ENSG00000091831 ESR1 ENSG00000142731 PLK4 H. sapiens SDL Slorth 0.982592 View
ENSG00000091831 ESR1 ENSG00000102038 SMARCA1 H. sapiens SDL Slorth 0.982585 View
ENSG00000087995 METTL2A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982573 View
ENSG00000091831 ESR1 ENSG00000119335 SET H. sapiens SDL Slorth 0.982553 View
ENSG00000091831 ESR1 ENSG00000175793 SFN H. sapiens SDL Slorth 0.982549 View
ENSG00000091831 ESR1 ENSG00000198400 NTRK1 H. sapiens SDL Slorth 0.982538 View
ENSG00000091831 ESR1 ENSG00000174738 NR1D2 H. sapiens SDL Slorth 0.982517 View
ENSG00000091831 ESR1 ENSG00000118513 MYB H. sapiens SDL Slorth 0.982504 View
ENSG00000091831 ESR1 ENSG00000159692 CTBP1 H. sapiens SDL Slorth 0.982503 View
ENSG00000091831 ESR1 ENSG00000147162 OGT H. sapiens SDL Slorth 0.982502 View
ENSG00000071242 RPS6KA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982501 View
ENSG00000091831 ESR1 ENSG00000103479 RBL2 H. sapiens SDL Slorth 0.982501 View
ENSG00000061918 GUCY1B3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982499 View
ENSG00000091831 ESR1 ENSG00000160789 LMNA H. sapiens SDL Slorth 0.982459 View
ENSG00000072422 RHOBTB1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982431 View
ENSG00000008853 RHOBTB2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.982431 View
ENSG00000091831 ESR1 ENSG00000135503 ACVR1B H. sapiens SDL Slorth 0.982431 View