ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000115677 HDLBP H. sapiens SDL Slorth 0.981548 View
ENSG00000091831 ESR1 ENSG00000111252 SH2B3 H. sapiens SDL Slorth 0.981518 View
ENSG00000091831 ESR1 ENSG00000126858 RHOT1 H. sapiens SDL Slorth 0.981514 View
ENSG00000091831 ESR1 ENSG00000101384 JAG1 H. sapiens SDL Slorth 0.981508 View
ENSG00000091831 ESR1 ENSG00000134014 ELP3 H. sapiens SDL Slorth 0.981492 View
ENSG00000091831 ESR1 ENSG00000168385 SEPT2 H. sapiens SDL Slorth 0.981481 View
ENSG00000077943 ITGA8 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981464 View
ENSG00000091831 ESR1 ENSG00000138448 ITGAV H. sapiens SDL Slorth 0.981449 View
ENSG00000091831 ESR1 ENSG00000121152 NCAPH H. sapiens SDL Slorth 0.981441 View
ENSG00000091831 ESR1 ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.981434 View
ENSG00000091831 ESR1 ENSG00000157077 ZFYVE9 H. sapiens SDL Slorth 0.981408 View
ENSG00000091831 ESR1 ENSG00000138778 CENPE H. sapiens SDL Slorth 0.981402 View
ENSG00000091831 ESR1 ENSG00000196419 XRCC6 H. sapiens SDL Slorth 0.981397 View
ENSG00000091831 ESR1 ENSG00000167986 DDB1 H. sapiens SDL Slorth 0.981387 View
ENSG00000063245 EPN1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981373 View
ENSG00000091831 ESR1 ENSG00000183020 AP2A2 H. sapiens SDL Slorth 0.981362 View
ENSG00000091831 ESR1 ENSG00000138095 LRPPRC H. sapiens SDL Slorth 0.981355 View
ENSG00000091831 ESR1 ENSG00000157456 CCNB2 H. sapiens SDL Slorth 0.981352 View
ENSG00000077264 PAK3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981338 View
ENSG00000087085 ACHE ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981338 View
ENSG00000091831 ESR1 ENSG00000196628 TCF4 H. sapiens SDL Slorth 0.981335 View
ENSG00000091831 ESR1 ENSG00000176749 CDK5R1 H. sapiens SDL Slorth 0.981333 View
ENSG00000091831 ESR1 ENSG00000109756 RAPGEF2 H. sapiens SDL Slorth 0.981326 View
ENSG00000091831 ESR1 ENSG00000092853 CLSPN H. sapiens SDL Slorth 0.981324 View
ENSG00000091831 ESR1 ENSG00000163902 RPN1 H. sapiens SDL Slorth 0.981311 View
ENSG00000091831 ESR1 ENSG00000136158 SPRY2 H. sapiens SDL Slorth 0.981299 View
ENSG00000091831 ESR1 ENSG00000103496 STX4 H. sapiens SDL Slorth 0.981295 View
ENSG00000091831 ESR1 ENSG00000144283 PKP4 H. sapiens SDL Slorth 0.981269 View
ENSG00000091831 ESR1 ENSG00000150907 FOXO1 H. sapiens SDL Slorth 0.981265 View
ENSG00000091831 ESR1 ENSG00000173207 CKS1B H. sapiens SDL Slorth 0.981249 View
ENSG00000091831 ESR1 ENSG00000135341 MAP3K7 H. sapiens SDL Slorth 0.981237 View
ENSG00000091831 ESR1 ENSG00000101057 MYBL2 H. sapiens SDL Slorth 0.981233 View
ENSG00000065534 MYLK ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981226 View
ENSG00000091831 ESR1 ENSG00000102010 BMX H. sapiens SDL Slorth 0.981225 View
ENSG00000091831 ESR1 ENSG00000196914 ARHGEF12 H. sapiens SDL Slorth 0.98122 View
ENSG00000091831 ESR1 ENSG00000131711 MAP1B H. sapiens SDL Slorth 0.981213 View
ENSG00000091831 ESR1 ENSG00000102900 NUP93 H. sapiens SDL Slorth 0.981207 View
ENSG00000034152 MAP2K3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981192 View
ENSG00000091831 ESR1 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.981188 View
ENSG00000091831 ESR1 ENSG00000120837 NFYB H. sapiens SDL Slorth 0.981177 View