ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000092841 MYL6 H. sapiens SDL Slorth 0.980398 View
ENSG00000091831 ESR1 ENSG00000143569 UBAP2L H. sapiens SDL Slorth 0.980398 View
ENSG00000091831 ESR1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.980381 View
ENSG00000091831 ESR1 ENSG00000198399 ITSN2 H. sapiens SDL Slorth 0.980381 View
ENSG00000091831 ESR1 ENSG00000156052 GNAQ H. sapiens SDL Slorth 0.980378 View
ENSG00000091831 ESR1 ENSG00000113282 CLINT1 H. sapiens SDL Slorth 0.980343 View
ENSG00000091831 ESR1 ENSG00000221914 PPP2R2A H. sapiens SDL Slorth 0.980335 View
ENSG00000091831 ESR1 ENSG00000138376 BARD1 H. sapiens SDL Slorth 0.980333 View
ENSG00000091831 ESR1 ENSG00000170248 PDCD6IP H. sapiens SDL Slorth 0.980326 View
ENSG00000091831 ESR1 ENSG00000120705 ETF1 H. sapiens SDL Slorth 0.980314 View
ENSG00000091831 ESR1 ENSG00000125971 DYNLRB1 H. sapiens SDL Slorth 0.980312 View
ENSG00000091831 ESR1 ENSG00000165025 SYK H. sapiens SDL Slorth 0.980309 View
ENSG00000091831 ESR1 ENSG00000167460 TPM4 H. sapiens SDL Slorth 0.980306 View
ENSG00000091831 ESR1 ENSG00000183072 NKX2-5 H. sapiens SDL Slorth 0.980299 View
ENSG00000091831 ESR1 ENSG00000183955 KMT5A H. sapiens SDL Slorth 0.980256 View
ENSG00000072694 FCGR2B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980255 View
ENSG00000091831 ESR1 ENSG00000117650 NEK2 H. sapiens SDL Slorth 0.980243 View
ENSG00000091831 ESR1 ENSG00000136717 BIN1 H. sapiens SDL Slorth 0.98023 View
ENSG00000067141 NEO1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980222 View
ENSG00000091831 ESR1 ENSG00000155097 ATP6V1C1 H. sapiens SDL Slorth 0.98022 View
ENSG00000076201 PTPN23 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.98022 View
ENSG00000091831 ESR1 ENSG00000149269 PAK1 H. sapiens SDL Slorth 0.980207 View
ENSG00000091831 ESR1 ENSG00000136826 KLF4 H. sapiens SDL Slorth 0.980183 View
ENSG00000075618 FSCN1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980183 View
ENSG00000011454 RABGAP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980165 View
ENSG00000091831 ESR1 ENSG00000197102 DYNC1H1 H. sapiens SDL Slorth 0.980161 View
ENSG00000091831 ESR1 ENSG00000198033 TUBA3C H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000155366 RHOC H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000174672 BRSK2 H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000107862 GBF1 H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000142945 KIF2C H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000133318 RTN3 H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000147130 ZMYM3 H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000125818 PSMF1 H. sapiens SDL Slorth 0.980143 View
ENSG00000091831 ESR1 ENSG00000178184 PARD6G H. sapiens SDL Slorth 0.98014 View
ENSG00000011132 APBA3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980128 View
ENSG00000091831 ESR1 ENSG00000135766 EGLN1 H. sapiens SDL Slorth 0.980115 View
ENSG00000091831 ESR1 ENSG00000108061 SHOC2 H. sapiens SDL Slorth 0.980113 View
ENSG00000091831 ESR1 ENSG00000126581 BECN1 H. sapiens SDL Slorth 0.980107 View
ENSG00000091831 ESR1 ENSG00000138081 FBXO11 H. sapiens SDL Slorth 0.980104 View