ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000159200 RCAN1 H. sapiens SDL Slorth 0.980788 View
ENSG00000091831 ESR1 ENSG00000105197 TIMM50 H. sapiens SDL Slorth 0.980787 View
ENSG00000051108 HERPUD1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980773 View
ENSG00000091831 ESR1 ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.980772 View
ENSG00000091831 ESR1 ENSG00000152086 TUBA3E H. sapiens SDL Slorth 0.980748 View
ENSG00000091831 ESR1 ENSG00000198900 TOP1 H. sapiens SDL Slorth 0.980746 View
ENSG00000091831 ESR1 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.98074 View
ENSG00000091831 ESR1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.980738 View
ENSG00000091831 ESR1 ENSG00000116560 SFPQ H. sapiens SDL Slorth 0.98073 View
ENSG00000091831 ESR1 ENSG00000164305 CASP3 H. sapiens SDL Slorth 0.980708 View
ENSG00000091831 ESR1 ENSG00000109606 DHX15 H. sapiens SDL Slorth 0.980697 View
ENSG00000091831 ESR1 ENSG00000180370 PAK2 H. sapiens SDL Slorth 0.980673 View
ENSG00000091831 ESR1 ENSG00000147140 NONO H. sapiens SDL Slorth 0.980672 View
ENSG00000091831 ESR1 ENSG00000119699 TGFB3 H. sapiens SDL Slorth 0.980672 View
ENSG00000091831 ESR1 ENSG00000096696 DSP H. sapiens SDL Slorth 0.980669 View
ENSG00000091831 ESR1 ENSG00000124795 DEK H. sapiens SDL Slorth 0.980656 View
ENSG00000091831 ESR1 ENSG00000173020 GRK2 H. sapiens SDL Slorth 0.980636 View
ENSG00000091831 ESR1 ENSG00000171456 ASXL1 H. sapiens SDL Slorth 0.980629 View
ENSG00000072501 SMC1A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980623 View
ENSG00000091831 ESR1 ENSG00000152284 TCF7L1 H. sapiens SDL Slorth 0.980595 View
ENSG00000073921 PICALM ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980579 View
ENSG00000091831 ESR1 ENSG00000185122 HSF1 H. sapiens SDL Slorth 0.980566 View
ENSG00000091831 ESR1 ENSG00000177272 KCNA3 H. sapiens SDL Slorth 0.980563 View
ENSG00000091831 ESR1 ENSG00000185104 FAF1 H. sapiens SDL Slorth 0.980563 View
ENSG00000091831 ESR1 ENSG00000126602 TRAP1 H. sapiens SDL Slorth 0.980556 View
ENSG00000091831 ESR1 ENSG00000131558 EXOC4 H. sapiens SDL Slorth 0.980551 View
ENSG00000091831 ESR1 ENSG00000102241 HTATSF1 H. sapiens SDL Slorth 0.98054 View
ENSG00000091831 ESR1 ENSG00000117758 STX12 H. sapiens SDL Slorth 0.980537 View
ENSG00000091831 ESR1 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.980534 View
ENSG00000091831 ESR1 ENSG00000170759 KIF5B H. sapiens SDL Slorth 0.980502 View
ENSG00000058272 PPP1R12A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980475 View
ENSG00000091831 ESR1 ENSG00000198087 CD2AP H. sapiens SDL Slorth 0.980459 View
ENSG00000091831 ESR1 ENSG00000177426 TGIF1 H. sapiens SDL Slorth 0.980447 View
ENSG00000091831 ESR1 ENSG00000166974 MAPRE2 H. sapiens SDL Slorth 0.980432 View
ENSG00000091831 ESR1 ENSG00000134899 ERCC5 H. sapiens SDL Slorth 0.980428 View
ENSG00000091831 ESR1 ENSG00000123143 PKN1 H. sapiens SDL Slorth 0.980426 View
ENSG00000078114 NEBL ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.980425 View
ENSG00000091831 ESR1 ENSG00000101945 SUV39H1 H. sapiens SDL Slorth 0.980419 View
ENSG00000091831 ESR1 ENSG00000120738 EGR1 H. sapiens SDL Slorth 0.980405 View
ENSG00000091831 ESR1 ENSG00000127314 RAP1B H. sapiens SDL Slorth 0.980403 View