ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000198258 UBL5 H. sapiens SDL Slorth 0.979172 View
ENSG00000091831 ESR1 ENSG00000125845 BMP2 H. sapiens SDL Slorth 0.979126 View
ENSG00000091831 ESR1 ENSG00000154928 EPHB1 H. sapiens SDL Slorth 0.979118 View
ENSG00000091831 ESR1 ENSG00000133104 SPG20 H. sapiens SDL Slorth 0.979108 View
ENSG00000091831 ESR1 ENSG00000238134 EHMT2 H. sapiens SDL Slorth 0.979101 View
ENSG00000091831 ESR1 ENSG00000116120 FARSB H. sapiens SDL Slorth 0.979091 View
ENSG00000091831 ESR1 ENSG00000126777 KTN1 H. sapiens SDL Slorth 0.979088 View
ENSG00000091831 ESR1 ENSG00000104738 MCM4 H. sapiens SDL Slorth 0.979082 View
ENSG00000091831 ESR1 ENSG00000196262 PPIA H. sapiens SDL Slorth 0.979067 View
ENSG00000091831 ESR1 ENSG00000099956 SMARCB1 H. sapiens SDL Slorth 0.979053 View
ENSG00000091831 ESR1 ENSG00000105329 TGFB1 H. sapiens SDL Slorth 0.979042 View
ENSG00000085185 BCORL1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979027 View
ENSG00000083290 ULK2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979015 View
ENSG00000091831 ESR1 ENSG00000116266 STXBP3 H. sapiens SDL Slorth 0.979013 View
ENSG00000091831 ESR1 ENSG00000105397 TYK2 H. sapiens SDL Slorth 0.979002 View
ENSG00000091831 ESR1 ENSG00000183454 GRIN2A H. sapiens SDL Slorth 0.978985 View
ENSG00000091831 ESR1 ENSG00000110321 EIF4G2 H. sapiens SDL Slorth 0.978985 View
ENSG00000078699 CBFA2T2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978984 View
ENSG00000091831 ESR1 ENSG00000171109 MFN1 H. sapiens SDL Slorth 0.978953 View
ENSG00000091831 ESR1 ENSG00000138757 G3BP2 H. sapiens SDL Slorth 0.978945 View
ENSG00000091831 ESR1 ENSG00000112742 TTK H. sapiens SDL Slorth 0.978923 View
ENSG00000091831 ESR1 ENSG00000145907 G3BP1 H. sapiens SDL Slorth 0.978896 View
ENSG00000091831 ESR1 ENSG00000177565 TBL1XR1 H. sapiens SDL Slorth 0.978891 View
ENSG00000091831 ESR1 ENSG00000148688 RPP30 H. sapiens SDL Slorth 0.978888 View
ENSG00000091831 ESR1 ENSG00000101109 STK4 H. sapiens SDL Slorth 0.978877 View
ENSG00000091831 ESR1 ENSG00000173542 MOB1B H. sapiens SDL Slorth 0.978876 View
ENSG00000091831 ESR1 ENSG00000197930 ERO1A H. sapiens SDL Slorth 0.978868 View
ENSG00000091831 ESR1 ENSG00000114650 SCAP H. sapiens SDL Slorth 0.978867 View
ENSG00000006468 ETV1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978867 View
ENSG00000091831 ESR1 ENSG00000134954 ETS1 H. sapiens SDL Slorth 0.978828 View
ENSG00000091831 ESR1 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.978812 View
ENSG00000091831 ESR1 ENSG00000121774 KHDRBS1 H. sapiens SDL Slorth 0.978799 View
ENSG00000091831 ESR1 ENSG00000181789 COPG1 H. sapiens SDL Slorth 0.978794 View
ENSG00000004848 ARX ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978779 View
ENSG00000080345 RIF1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978763 View
ENSG00000091831 ESR1 ENSG00000213585 VDAC1 H. sapiens SDL Slorth 0.978749 View
ENSG00000091831 ESR1 ENSG00000158604 TMED4 H. sapiens SDL Slorth 0.978727 View
ENSG00000037757 MRI1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978718 View
ENSG00000067900 ROCK1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978701 View
ENSG00000076321 KLHL20 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978682 View