ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000123358 NR4A1 H. sapiens SDL Slorth 0.978223 View
ENSG00000091831 ESR1 ENSG00000131899 LLGL1 H. sapiens SDL Slorth 0.978219 View
ENSG00000072364 AFF4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978193 View
ENSG00000091831 ESR1 ENSG00000152104 PTPN14 H. sapiens SDL Slorth 0.978192 View
ENSG00000091831 ESR1 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.978189 View
ENSG00000091831 ESR1 ENSG00000163029 SMC6 H. sapiens SDL Slorth 0.978176 View
ENSG00000029534 ANK1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97817 View
ENSG00000091831 ESR1 ENSG00000147416 ATP6V1B2 H. sapiens SDL Slorth 0.978167 View
ENSG00000091831 ESR1 ENSG00000134086 VHL H. sapiens SDL Slorth 0.978156 View
ENSG00000091831 ESR1 ENSG00000135476 ESPL1 H. sapiens SDL Slorth 0.978126 View
ENSG00000091831 ESR1 ENSG00000186716 BCR H. sapiens SDL Slorth 0.978111 View
ENSG00000091831 ESR1 ENSG00000137193 PIM1 H. sapiens SDL Slorth 0.978109 View
ENSG00000091831 ESR1 ENSG00000151729 SLC25A4 H. sapiens SDL Slorth 0.978109 View
ENSG00000091831 ESR1 ENSG00000254445 HSPB2-C11orf52 H. sapiens SDL Slorth 0.978079 View
ENSG00000087470 DNM1L ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978078 View
ENSG00000087460 GNAS ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978074 View
ENSG00000091831 ESR1 ENSG00000132906 CASP9 H. sapiens SDL Slorth 0.978026 View
ENSG00000091831 ESR1 ENSG00000113368 LMNB1 H. sapiens SDL Slorth 0.978013 View
ENSG00000091831 ESR1 ENSG00000170296 GABARAP H. sapiens SDL Slorth 0.977988 View
ENSG00000091831 ESR1 ENSG00000105993 DNAJB6 H. sapiens SDL Slorth 0.977912 View
ENSG00000091831 ESR1 ENSG00000158022 TRIM63 H. sapiens SDL Slorth 0.977861 View
ENSG00000091831 ESR1 ENSG00000152256 PDK1 H. sapiens SDL Slorth 0.977844 View
ENSG00000091831 ESR1 ENSG00000167118 URM1 H. sapiens SDL Slorth 0.97784 View
ENSG00000091831 ESR1 ENSG00000101224 CDC25B H. sapiens SDL Slorth 0.977838 View
ENSG00000020633 RUNX3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977834 View
ENSG00000070770 CSNK2A2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977787 View
ENSG00000091831 ESR1 ENSG00000213465 ARL2 H. sapiens SDL Slorth 0.977781 View
ENSG00000091831 ESR1 ENSG00000188906 LRRK2 H. sapiens SDL Slorth 0.977774 View
ENSG00000091831 ESR1 ENSG00000134308 YWHAQ H. sapiens SDL Slorth 0.977768 View
ENSG00000091831 ESR1 ENSG00000105229 PIAS4 H. sapiens SDL Slorth 0.977765 View
ENSG00000091831 ESR1 ENSG00000164548 TRA2A H. sapiens SDL Slorth 0.977747 View
ENSG00000091831 ESR1 ENSG00000172059 KLF11 H. sapiens SDL Slorth 0.977742 View
ENSG00000091831 ESR1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.977722 View
ENSG00000091831 ESR1 ENSG00000100077 GRK3 H. sapiens SDL Slorth 0.977671 View
ENSG00000091831 ESR1 ENSG00000174903 RAB1B H. sapiens SDL Slorth 0.977663 View
ENSG00000048392 RRM2B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977631 View
ENSG00000091831 ESR1 ENSG00000197451 HNRNPAB H. sapiens SDL Slorth 0.977612 View
ENSG00000091831 ESR1 ENSG00000185236 RAB11B H. sapiens SDL Slorth 0.977602 View
ENSG00000075340 ADD2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977559 View
ENSG00000063660 GPC1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977559 View