ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000128340 RAC2 H. sapiens SDL Slorth 0.976954 View
ENSG00000091831 ESR1 ENSG00000170734 POLH H. sapiens SDL Slorth 0.976952 View
ENSG00000091831 ESR1 ENSG00000175054 ATR H. sapiens SDL Slorth 0.976925 View
ENSG00000064393 HIPK2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.9769 View
ENSG00000037280 FLT4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976874 View
ENSG00000091831 ESR1 ENSG00000141404 GNAL H. sapiens SDL Slorth 0.976872 View
ENSG00000065243 PKN2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976868 View
ENSG00000008196 TFAP2B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976853 View
ENSG00000091831 ESR1 ENSG00000118046 STK11 H. sapiens SDL Slorth 0.976819 View
ENSG00000091831 ESR1 ENSG00000197694 SPTAN1 H. sapiens SDL Slorth 0.976815 View
ENSG00000064703 DDX20 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976744 View
ENSG00000091831 ESR1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.976718 View
ENSG00000091831 ESR1 ENSG00000143878 RHOB H. sapiens SDL Slorth 0.976706 View
ENSG00000072134 EPN2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976697 View
ENSG00000047849 MAP4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976697 View
ENSG00000091831 ESR1 ENSG00000112531 QKI H. sapiens SDL Slorth 0.97669 View
ENSG00000091831 ESR1 ENSG00000102898 NUTF2 H. sapiens SDL Slorth 0.976659 View
ENSG00000066777 ARFGEF1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976657 View
ENSG00000091831 ESR1 ENSG00000158290 CUL4B H. sapiens SDL Slorth 0.976657 View
ENSG00000028277 POU2F2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976654 View
ENSG00000070476 ZXDC ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976637 View
ENSG00000070882 OSBPL3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976615 View
ENSG00000091831 ESR1 ENSG00000167815 PRDX2 H. sapiens SDL Slorth 0.976611 View
ENSG00000017797 RALBP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976579 View
ENSG00000091831 ESR1 ENSG00000136504 KAT7 H. sapiens SDL Slorth 0.976564 View
ENSG00000091831 ESR1 ENSG00000183337 BCOR H. sapiens SDL Slorth 0.976564 View
ENSG00000091831 ESR1 ENSG00000100347 SAMM50 H. sapiens SDL Slorth 0.97654 View
ENSG00000091831 ESR1 ENSG00000147274 RBMX H. sapiens SDL Slorth 0.976539 View
ENSG00000091831 ESR1 ENSG00000198176 TFDP1 H. sapiens SDL Slorth 0.976526 View
ENSG00000091831 ESR1 ENSG00000100281 HMGXB4 H. sapiens SDL Slorth 0.976456 View
ENSG00000058091 CDK14 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976456 View
ENSG00000091831 ESR1 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.976382 View
ENSG00000091831 ESR1 ENSG00000118260 CREB1 H. sapiens SDL Slorth 0.976338 View
ENSG00000091831 ESR1 ENSG00000167461 RAB8A H. sapiens SDL Slorth 0.976305 View
ENSG00000091831 ESR1 ENSG00000100503 NIN H. sapiens SDL Slorth 0.976292 View
ENSG00000091831 ESR1 ENSG00000198373 WWP2 H. sapiens SDL Slorth 0.976277 View
ENSG00000091831 ESR1 ENSG00000197081 IGF2R H. sapiens SDL Slorth 0.976276 View
ENSG00000091831 ESR1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.97625 View
ENSG00000091831 ESR1 ENSG00000101199 ARFGAP1 H. sapiens SDL Slorth 0.976245 View
ENSG00000091831 ESR1 ENSG00000164327 RICTOR H. sapiens SDL Slorth 0.976244 View