ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000116288 PARK7 H. sapiens SDL Slorth 0.973996 View
ENSG00000091831 ESR1 ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.973981 View
ENSG00000007866 TEAD3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973976 View
ENSG00000091831 ESR1 ENSG00000144118 RALB H. sapiens SDL Slorth 0.973963 View
ENSG00000091831 ESR1 ENSG00000165699 TSC1 H. sapiens SDL Slorth 0.973953 View
ENSG00000091831 ESR1 ENSG00000114423 CBLB H. sapiens SDL Slorth 0.973949 View
ENSG00000091831 ESR1 ENSG00000100462 PRMT5 H. sapiens SDL Slorth 0.973941 View
ENSG00000091831 ESR1 ENSG00000167996 FTH1 H. sapiens SDL Slorth 0.973929 View
ENSG00000091831 ESR1 ENSG00000124207 CSE1L H. sapiens SDL Slorth 0.973928 View
ENSG00000086200 IPO11 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973909 View
ENSG00000091831 ESR1 ENSG00000125257 ABCC4 H. sapiens SDL Slorth 0.9739 View
ENSG00000091831 ESR1 ENSG00000136758 YME1L1 H. sapiens SDL Slorth 0.973899 View
ENSG00000091831 ESR1 ENSG00000133704 IPO8 H. sapiens SDL Slorth 0.973862 View
ENSG00000091831 ESR1 ENSG00000123131 PRDX4 H. sapiens SDL Slorth 0.973862 View
ENSG00000091831 ESR1 ENSG00000171094 ALK H. sapiens SDL Slorth 0.973862 View
ENSG00000091831 ESR1 ENSG00000128591 FLNC H. sapiens SDL Slorth 0.973839 View
ENSG00000091831 ESR1 ENSG00000158402 CDC25C H. sapiens SDL Slorth 0.973826 View
ENSG00000091831 ESR1 ENSG00000186575 NF2 H. sapiens SDL Slorth 0.973811 View
ENSG00000091831 ESR1 ENSG00000198836 OPA1 H. sapiens SDL Slorth 0.973803 View
ENSG00000091831 ESR1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.973785 View
ENSG00000091831 ESR1 ENSG00000128245 YWHAH H. sapiens SDL Slorth 0.973782 View
ENSG00000091831 ESR1 ENSG00000131507 NDFIP1 H. sapiens SDL Slorth 0.973758 View
ENSG00000091831 ESR1 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.973732 View
ENSG00000091831 ESR1 ENSG00000196296 ATP2A1 H. sapiens SDL Slorth 0.973722 View
ENSG00000091831 ESR1 ENSG00000113569 NUP155 H. sapiens SDL Slorth 0.973717 View
ENSG00000063438 AHRR ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973707 View
ENSG00000091831 ESR1 ENSG00000111087 GLI1 H. sapiens SDL Slorth 0.973703 View
ENSG00000091831 ESR1 ENSG00000168374 ARF4 H. sapiens SDL Slorth 0.973703 View
ENSG00000091831 ESR1 ENSG00000120694 HSPH1 H. sapiens SDL Slorth 0.973703 View
ENSG00000086758 HUWE1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973599 View
ENSG00000005893 LAMP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973595 View
ENSG00000091831 ESR1 ENSG00000154582 TCEB1 H. sapiens SDL Slorth 0.973584 View
ENSG00000091831 ESR1 ENSG00000149311 ATM H. sapiens SDL Slorth 0.973572 View
ENSG00000077150 NFKB2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973563 View
ENSG00000091831 ESR1 ENSG00000166484 MAPK7 H. sapiens SDL Slorth 0.973556 View
ENSG00000091106 NLRC4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973554 View
ENSG00000075826 SEC31B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973528 View
ENSG00000091831 ESR1 ENSG00000162736 NCSTN H. sapiens SDL Slorth 0.973499 View
ENSG00000091831 ESR1 ENSG00000117318 ID3 H. sapiens SDL Slorth 0.973499 View
ENSG00000048052 HDAC9 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973457 View