ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000100596 SPTLC2 H. sapiens SDL Slorth 0.974641 View
ENSG00000007944 MYLIP ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974633 View
ENSG00000091831 ESR1 ENSG00000188603 CLN3 H. sapiens SDL Slorth 0.974615 View
ENSG00000091831 ESR1 ENSG00000103653 CSK H. sapiens SDL Slorth 0.974615 View
ENSG00000091831 ESR1 ENSG00000168209 DDIT4 H. sapiens SDL Slorth 0.974594 View
ENSG00000091831 ESR1 ENSG00000132361 CLUH H. sapiens SDL Slorth 0.974594 View
ENSG00000091831 ESR1 ENSG00000184900 SUMO3 H. sapiens SDL Slorth 0.974584 View
ENSG00000091831 ESR1 ENSG00000173402 DAG1 H. sapiens SDL Slorth 0.974578 View
ENSG00000091831 ESR1 ENSG00000157557 ETS2 H. sapiens SDL Slorth 0.974578 View
ENSG00000091831 ESR1 ENSG00000268173 AC007192.4 H. sapiens SDL Slorth 0.974563 View
ENSG00000091831 ESR1 ENSG00000155363 MOV10 H. sapiens SDL Slorth 0.974525 View
ENSG00000091831 ESR1 ENSG00000108055 SMC3 H. sapiens SDL Slorth 0.974493 View
ENSG00000091831 ESR1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.974492 View
ENSG00000084764 MAPRE3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974489 View
ENSG00000091831 ESR1 ENSG00000125952 MAX H. sapiens SDL Slorth 0.974482 View
ENSG00000091831 ESR1 ENSG00000169439 SDC2 H. sapiens SDL Slorth 0.974448 View
ENSG00000091831 ESR1 ENSG00000204843 DCTN1 H. sapiens SDL Slorth 0.97443 View
ENSG00000091831 ESR1 ENSG00000141968 VAV1 H. sapiens SDL Slorth 0.974362 View
ENSG00000091409 ITGA6 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974353 View
ENSG00000091831 ESR1 ENSG00000108587 GOSR1 H. sapiens SDL Slorth 0.974353 View
ENSG00000081189 MEF2C ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974284 View
ENSG00000091831 ESR1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.974282 View
ENSG00000091831 ESR1 ENSG00000239672 NME1 H. sapiens SDL Slorth 0.974262 View
ENSG00000091831 ESR1 ENSG00000104852 SNRNP70 H. sapiens SDL Slorth 0.974245 View
ENSG00000091831 ESR1 ENSG00000138160 KIF11 H. sapiens SDL Slorth 0.974241 View
ENSG00000091831 ESR1 ENSG00000173110 HSPA6 H. sapiens SDL Slorth 0.97424 View
ENSG00000091831 ESR1 ENSG00000110172 CHORDC1 H. sapiens SDL Slorth 0.974233 View
ENSG00000072315 TRPC5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974194 View
ENSG00000091831 ESR1 ENSG00000198625 MDM4 H. sapiens SDL Slorth 0.974189 View
ENSG00000091831 ESR1 ENSG00000138814 PPP3CA H. sapiens SDL Slorth 0.974188 View
ENSG00000082258 CCNT2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974138 View
ENSG00000010818 HIVEP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974109 View
ENSG00000091831 ESR1 ENSG00000140682 TGFB1I1 H. sapiens SDL Slorth 0.97408 View
ENSG00000051382 PIK3CB ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974079 View
ENSG00000087510 TFAP2C ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974047 View
ENSG00000091831 ESR1 ENSG00000160007 ARHGAP35 H. sapiens SDL Slorth 0.974039 View
ENSG00000091831 ESR1 ENSG00000215301 DDX3X H. sapiens SDL Slorth 0.974036 View
ENSG00000091831 ESR1 ENSG00000164402 SEPT8 H. sapiens SDL Slorth 0.974024 View
ENSG00000091831 ESR1 ENSG00000107796 ACTA2 H. sapiens SDL Slorth 0.974022 View
ENSG00000091831 ESR1 ENSG00000211455 STK38L H. sapiens SDL Slorth 0.973996 View