ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000078674 PCM1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97344 View
ENSG00000005156 LIG3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973426 View
ENSG00000091831 ESR1 ENSG00000121481 RNF2 H. sapiens SDL Slorth 0.973399 View
ENSG00000091831 ESR1 ENSG00000092108 SCFD1 H. sapiens SDL Slorth 0.973382 View
ENSG00000004487 KDM1A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973376 View
ENSG00000079819 EPB41L2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973359 View
ENSG00000091831 ESR1 ENSG00000131196 NFATC1 H. sapiens SDL Slorth 0.973357 View
ENSG00000091831 ESR1 ENSG00000122565 CBX3 H. sapiens SDL Slorth 0.97335 View
ENSG00000091831 ESR1 ENSG00000140992 PDPK1 H. sapiens SDL Slorth 0.973339 View
ENSG00000091831 ESR1 ENSG00000120948 TARDBP H. sapiens SDL Slorth 0.973304 View
ENSG00000091831 ESR1 ENSG00000127511 SIN3B H. sapiens SDL Slorth 0.973229 View
ENSG00000091831 ESR1 ENSG00000162613 FUBP1 H. sapiens SDL Slorth 0.973218 View
ENSG00000091831 ESR1 ENSG00000101213 PTK6 H. sapiens SDL Slorth 0.973199 View
ENSG00000091831 ESR1 ENSG00000141564 RPTOR H. sapiens SDL Slorth 0.973176 View
ENSG00000091831 ESR1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.97316 View
ENSG00000091831 ESR1 ENSG00000143190 POU2F1 H. sapiens SDL Slorth 0.973152 View
ENSG00000091831 ESR1 ENSG00000187608 ISG15 H. sapiens SDL Slorth 0.973148 View
ENSG00000091831 ESR1 ENSG00000141837 CACNA1A H. sapiens SDL Slorth 0.973129 View
ENSG00000082641 NFE2L1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.973105 View
ENSG00000091831 ESR1 ENSG00000100968 NFATC4 H. sapiens SDL Slorth 0.973061 View
ENSG00000091831 ESR1 ENSG00000112062 MAPK14 H. sapiens SDL Slorth 0.973033 View
ENSG00000091831 ESR1 ENSG00000101266 CSNK2A1 H. sapiens SDL Slorth 0.973026 View
ENSG00000091831 ESR1 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.972994 View
ENSG00000091831 ESR1 ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.972985 View
ENSG00000091831 ESR1 ENSG00000124784 RIOK1 H. sapiens SDL Slorth 0.972985 View
ENSG00000091831 ESR1 ENSG00000172845 SP3 H. sapiens SDL Slorth 0.972982 View
ENSG00000091831 ESR1 ENSG00000156970 BUB1B H. sapiens SDL Slorth 0.972969 View
ENSG00000091831 ESR1 ENSG00000160224 AIRE H. sapiens SDL Slorth 0.972962 View
ENSG00000091831 ESR1 ENSG00000177084 POLE H. sapiens SDL Slorth 0.972952 View
ENSG00000091831 ESR1 ENSG00000159216 RUNX1 H. sapiens SDL Slorth 0.972931 View
ENSG00000091831 ESR1 ENSG00000170345 FOS H. sapiens SDL Slorth 0.972913 View
ENSG00000091831 ESR1 ENSG00000101972 STAG2 H. sapiens SDL Slorth 0.972891 View
ENSG00000091831 ESR1 ENSG00000118503 TNFAIP3 H. sapiens SDL Slorth 0.972888 View
ENSG00000091831 ESR1 ENSG00000100664 EIF5 H. sapiens SDL Slorth 0.972886 View
ENSG00000091831 ESR1 ENSG00000128191 DGCR8 H. sapiens SDL Slorth 0.972884 View
ENSG00000091831 ESR1 ENSG00000178950 GAK H. sapiens SDL Slorth 0.972857 View
ENSG00000091831 ESR1 ENSG00000105486 LIG1 H. sapiens SDL Slorth 0.972851 View
ENSG00000076108 BAZ2A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972845 View
ENSG00000091831 ESR1 ENSG00000110395 CBL H. sapiens SDL Slorth 0.972837 View
ENSG00000090376 IRAK3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972798 View