ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000028528 SNX1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971263 View
ENSG00000091831 ESR1 ENSG00000163110 PDLIM5 H. sapiens SDL Slorth 0.971253 View
ENSG00000091831 ESR1 ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.971236 View
ENSG00000091831 ESR1 ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.971204 View
ENSG00000091831 ESR1 ENSG00000213066 FGFR1OP H. sapiens SDL Slorth 0.971189 View
ENSG00000091831 ESR1 ENSG00000148943 LIN7C H. sapiens SDL Slorth 0.971141 View
ENSG00000091831 ESR1 ENSG00000119314 PTBP3 H. sapiens SDL Slorth 0.971095 View
ENSG00000075711 DLG1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971095 View
ENSG00000091831 ESR1 ENSG00000133216 EPHB2 H. sapiens SDL Slorth 0.971076 View
ENSG00000024048 UBR2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971028 View
ENSG00000013375 PGM3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971011 View
ENSG00000005194 CIAPIN1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971003 View
ENSG00000091831 ESR1 ENSG00000181163 NPM1 H. sapiens SDL Slorth 0.970939 View
ENSG00000091831 ESR1 ENSG00000114867 EIF4G1 H. sapiens SDL Slorth 0.97092 View
ENSG00000091831 ESR1 ENSG00000151532 VTI1A H. sapiens SDL Slorth 0.970811 View
ENSG00000091831 ESR1 ENSG00000142168 SOD1 H. sapiens SDL Slorth 0.970774 View
ENSG00000091831 ESR1 ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.970731 View
ENSG00000088808 PPP1R13B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970709 View
ENSG00000091831 ESR1 ENSG00000103769 RAB11A H. sapiens SDL Slorth 0.970692 View
ENSG00000091831 ESR1 ENSG00000122545 SEPT7 H. sapiens SDL Slorth 0.970691 View
ENSG00000091831 ESR1 ENSG00000164466 SFXN1 H. sapiens SDL Slorth 0.970672 View
ENSG00000091831 ESR1 ENSG00000116141 MARK1 H. sapiens SDL Slorth 0.970662 View
ENSG00000087263 OGFOD1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970656 View
ENSG00000091831 ESR1 ENSG00000168214 RBPJ H. sapiens SDL Slorth 0.97064 View
ENSG00000091831 ESR1 ENSG00000178921 PFAS H. sapiens SDL Slorth 0.97062 View
ENSG00000091831 ESR1 ENSG00000163655 GMPS H. sapiens SDL Slorth 0.970618 View
ENSG00000062485 CS ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970609 View
ENSG00000091831 ESR1 ENSG00000099817 POLR2E H. sapiens SDL Slorth 0.970592 View
ENSG00000049246 PER3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97059 View
ENSG00000071794 HLTF ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970569 View
ENSG00000091831 ESR1 ENSG00000169714 CNBP H. sapiens SDL Slorth 0.970552 View
ENSG00000091831 ESR1 ENSG00000139719 VPS33A H. sapiens SDL Slorth 0.970551 View
ENSG00000086065 CHMP5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970518 View
ENSG00000091831 ESR1 ENSG00000134057 CCNB1 H. sapiens SDL Slorth 0.970462 View
ENSG00000091831 ESR1 ENSG00000159251 ACTC1 H. sapiens SDL Slorth 0.970449 View
ENSG00000091831 ESR1 ENSG00000144867 SRPRB H. sapiens SDL Slorth 0.970411 View
ENSG00000070778 PTPN21 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970387 View
ENSG00000091831 ESR1 ENSG00000124164 VAPB H. sapiens SDL Slorth 0.970387 View
ENSG00000079805 DNM2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970378 View
ENSG00000091831 ESR1 ENSG00000105568 PPP2R1A H. sapiens SDL Slorth 0.970351 View