ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000115267 IFIH1 H. sapiens SDL Slorth 0.970096 View
ENSG00000091831 ESR1 ENSG00000186153 WWOX H. sapiens SDL Slorth 0.970091 View
ENSG00000091831 ESR1 ENSG00000174437 ATP2A2 H. sapiens SDL Slorth 0.970084 View
ENSG00000049245 VAMP3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970017 View
ENSG00000034677 RNF19A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970003 View
ENSG00000091831 ESR1 ENSG00000101966 XIAP H. sapiens SDL Slorth 0.969982 View
ENSG00000091831 ESR1 ENSG00000166913 YWHAB H. sapiens SDL Slorth 0.969967 View
ENSG00000091831 ESR1 ENSG00000101811 CSTF2 H. sapiens SDL Slorth 0.969966 View
ENSG00000057657 PRDM1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969954 View
ENSG00000091073 DTX2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969954 View
ENSG00000091831 ESR1 ENSG00000183570 PCBP3 H. sapiens SDL Slorth 0.969952 View
ENSG00000091831 ESR1 ENSG00000177688 SUMO4 H. sapiens SDL Slorth 0.969949 View
ENSG00000091831 ESR1 ENSG00000188229 TUBB4B H. sapiens SDL Slorth 0.969925 View
ENSG00000056097 ZFR ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969911 View
ENSG00000091831 ESR1 ENSG00000114125 RNF7 H. sapiens SDL Slorth 0.969905 View
ENSG00000049759 NEDD4L ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969884 View
ENSG00000091831 ESR1 ENSG00000117450 PRDX1 H. sapiens SDL Slorth 0.969837 View
ENSG00000091831 ESR1 ENSG00000101003 GINS1 H. sapiens SDL Slorth 0.969836 View
ENSG00000004975 DVL2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969834 View
ENSG00000091831 ESR1 ENSG00000112118 MCM3 H. sapiens SDL Slorth 0.969833 View
ENSG00000091831 ESR1 ENSG00000115129 TP53I3 H. sapiens SDL Slorth 0.969822 View
ENSG00000091831 ESR1 ENSG00000103222 ABCC1 H. sapiens SDL Slorth 0.969806 View
ENSG00000091831 ESR1 ENSG00000144645 OSBPL10 H. sapiens SDL Slorth 0.969804 View
ENSG00000091831 ESR1 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.969771 View
ENSG00000091831 ESR1 ENSG00000172936 MYD88 H. sapiens SDL Slorth 0.969708 View
ENSG00000091831 ESR1 ENSG00000109189 USP46 H. sapiens SDL Slorth 0.969698 View
ENSG00000079102 RUNX1T1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969664 View
ENSG00000091831 ESR1 ENSG00000183495 EP400 H. sapiens SDL Slorth 0.969658 View
ENSG00000091831 ESR1 ENSG00000110713 NUP98 H. sapiens SDL Slorth 0.969621 View
ENSG00000085382 HACE1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.9696 View
ENSG00000019582 CD74 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.96958 View
ENSG00000073282 TP63 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969568 View
ENSG00000091831 ESR1 ENSG00000166224 SGPL1 H. sapiens SDL Slorth 0.969563 View
ENSG00000091831 ESR1 ENSG00000151292 CSNK1G3 H. sapiens SDL Slorth 0.96955 View
ENSG00000091831 ESR1 ENSG00000126453 BCL2L12 H. sapiens SDL Slorth 0.96955 View
ENSG00000072958 AP1M1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969533 View
ENSG00000080603 SRCAP ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969533 View
ENSG00000091831 ESR1 ENSG00000198742 SMURF1 H. sapiens SDL Slorth 0.969531 View
ENSG00000065361 ERBB3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.96949 View
ENSG00000091831 ESR1 ENSG00000108559 NUP88 H. sapiens SDL Slorth 0.969453 View