ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000085832 EPS15 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968143 View
ENSG00000084234 APLP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968142 View
ENSG00000091831 ESR1 ENSG00000169813 HNRNPF H. sapiens SDL Slorth 0.968108 View
ENSG00000091831 ESR1 ENSG00000146425 DYNLT1 H. sapiens SDL Slorth 0.968073 View
ENSG00000076944 STXBP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968069 View
ENSG00000091831 ESR1 ENSG00000204120 GIGYF2 H. sapiens SDL Slorth 0.968069 View
ENSG00000091831 ESR1 ENSG00000109971 HSPA8 H. sapiens SDL Slorth 0.968058 View
ENSG00000091831 ESR1 ENSG00000122218 COPA H. sapiens SDL Slorth 0.968058 View
ENSG00000091831 ESR1 ENSG00000102554 KLF5 H. sapiens SDL Slorth 0.968045 View
ENSG00000091831 ESR1 ENSG00000169032 MAP2K1 H. sapiens SDL Slorth 0.968002 View
ENSG00000042088 TDP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.96792 View
ENSG00000091831 ESR1 ENSG00000124535 WRNIP1 H. sapiens SDL Slorth 0.967911 View
ENSG00000091831 ESR1 ENSG00000132964 CDK8 H. sapiens SDL Slorth 0.967887 View
ENSG00000091831 ESR1 ENSG00000141552 ANAPC11 H. sapiens SDL Slorth 0.967863 View
ENSG00000091831 ESR1 ENSG00000104812 GYS1 H. sapiens SDL Slorth 0.967862 View
ENSG00000091831 ESR1 ENSG00000182944 EWSR1 H. sapiens SDL Slorth 0.967859 View
ENSG00000091831 ESR1 ENSG00000107581 EIF3A H. sapiens SDL Slorth 0.967832 View
ENSG00000091831 ESR1 ENSG00000172725 CORO1B H. sapiens SDL Slorth 0.967826 View
ENSG00000091831 ESR1 ENSG00000112658 SRF H. sapiens SDL Slorth 0.967782 View
ENSG00000082014 SMARCD3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.967759 View
ENSG00000091831 ESR1 ENSG00000105723 GSK3A H. sapiens SDL Slorth 0.967721 View
ENSG00000091831 ESR1 ENSG00000164045 CDC25A H. sapiens SDL Slorth 0.967691 View
ENSG00000091831 ESR1 ENSG00000179094 PER1 H. sapiens SDL Slorth 0.967664 View
ENSG00000054118 THRAP3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.967654 View
ENSG00000019549 SNAI2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.967639 View
ENSG00000091831 ESR1 ENSG00000153201 RANBP2 H. sapiens SDL Slorth 0.967618 View
ENSG00000071539 TRIP13 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.96761 View
ENSG00000074181 NOTCH3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.967603 View
ENSG00000091831 ESR1 ENSG00000094804 CDC6 H. sapiens SDL Slorth 0.967591 View
ENSG00000090273 NUDC ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.967494 View
ENSG00000091831 ESR1 ENSG00000120733 KDM3B H. sapiens SDL Slorth 0.967468 View
ENSG00000091831 ESR1 ENSG00000105402 NAPA H. sapiens SDL Slorth 0.967454 View
ENSG00000091831 ESR1 ENSG00000145632 PLK2 H. sapiens SDL Slorth 0.967447 View
ENSG00000091831 ESR1 ENSG00000103197 TSC2 H. sapiens SDL Slorth 0.967413 View
ENSG00000091831 ESR1 ENSG00000105325 FZR1 H. sapiens SDL Slorth 0.967402 View
ENSG00000067715 SYT1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.967357 View
ENSG00000091831 ESR1 ENSG00000131165 CHMP1A H. sapiens SDL Slorth 0.967347 View
ENSG00000091831 ESR1 ENSG00000140396 NCOA2 H. sapiens SDL Slorth 0.967326 View
ENSG00000091831 ESR1 ENSG00000276618 RAD17 H. sapiens SDL Slorth 0.967168 View
ENSG00000091831 ESR1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.967158 View