ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000180098 TRNAU1AP H. sapiens SDL Slorth 0.964265 View
ENSG00000018625 ATP1A2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964214 View
ENSG00000070961 ATP2B1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964214 View
ENSG00000090776 EFNB1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964214 View
ENSG00000085563 ABCB1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964214 View
ENSG00000091831 ESR1 ENSG00000196531 NACA H. sapiens SDL Slorth 0.964191 View
ENSG00000091831 ESR1 ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.964184 View
ENSG00000091831 ESR1 ENSG00000135903 PAX3 H. sapiens SDL Slorth 0.96415 View
ENSG00000091831 ESR1 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.964095 View
ENSG00000091831 ESR1 ENSG00000105146 AURKC H. sapiens SDL Slorth 0.964086 View
ENSG00000091831 ESR1 ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.964082 View
ENSG00000091831 ESR1 ENSG00000130332 LSM7 H. sapiens SDL Slorth 0.964059 View
ENSG00000077522 ACTN2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964025 View
ENSG00000091831 ESR1 ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.963905 View
ENSG00000091831 ESR1 ENSG00000148484 RSU1 H. sapiens SDL Slorth 0.96384 View
ENSG00000091831 ESR1 ENSG00000196576 PLXNB2 H. sapiens SDL Slorth 0.963834 View
ENSG00000091831 ESR1 ENSG00000113595 TRIM23 H. sapiens SDL Slorth 0.963818 View
ENSG00000091831 ESR1 ENSG00000115902 SLC1A4 H. sapiens SDL Slorth 0.963797 View
ENSG00000091831 ESR1 ENSG00000103657 HERC1 H. sapiens SDL Slorth 0.963797 View
ENSG00000091831 ESR1 ENSG00000123983 ACSL3 H. sapiens SDL Slorth 0.963797 View
ENSG00000091831 ESR1 ENSG00000160746 ANO10 H. sapiens SDL Slorth 0.963797 View
ENSG00000091831 ESR1 ENSG00000106348 IMPDH1 H. sapiens SDL Slorth 0.963797 View
ENSG00000091831 ESR1 ENSG00000110330 BIRC2 H. sapiens SSL Slorth 0.963795 View
ENSG00000091831 ESR1 ENSG00000100906 NFKBIA H. sapiens SDL Slorth 0.963788 View
ENSG00000091831 ESR1 ENSG00000156603 MED19 H. sapiens SDL Slorth 0.963782 View
ENSG00000091831 ESR1 ENSG00000108443 RPS6KB1 H. sapiens SDL Slorth 0.963701 View
ENSG00000076984 MAP2K7 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.963701 View
ENSG00000091831 ESR1 ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.963604 View
ENSG00000091831 ESR1 ENSG00000137692 DCUN1D5 H. sapiens SDL Slorth 0.963593 View
ENSG00000089876 DHX32 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.963581 View
ENSG00000091127 PUS7 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.963581 View
ENSG00000079739 PGM1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.963581 View
ENSG00000079332 SAR1A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.963581 View
ENSG00000069849 ATP1B3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.963581 View
ENSG00000091483 FH ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.963581 View
ENSG00000091831 ESR1 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.963579 View
ENSG00000091831 ESR1 ENSG00000138029 HADHB H. sapiens SDL Slorth 0.963548 View
ENSG00000091831 ESR1 ENSG00000135829 DHX9 H. sapiens SDL Slorth 0.963508 View
ENSG00000091831 ESR1 ENSG00000135829 DHX9 H. sapiens SSL Slorth 0.963489 View
ENSG00000091831 ESR1 ENSG00000092201 SUPT16H H. sapiens SSL Slorth 0.963419 View