ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000132388 UBE2G1 H. sapiens SDL Slorth 0.967083 View
ENSG00000013561 RNF14 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.967042 View
ENSG00000091831 ESR1 ENSG00000097033 SH3GLB1 H. sapiens SDL Slorth 0.966967 View
ENSG00000048462 TNFRSF17 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966954 View
ENSG00000075413 MARK3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966948 View
ENSG00000091831 ESR1 ENSG00000166501 PRKCB H. sapiens SDL Slorth 0.966937 View
ENSG00000074266 EED ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966937 View
ENSG00000091831 ESR1 ENSG00000109906 ZBTB16 H. sapiens SDL Slorth 0.966937 View
ENSG00000091831 ESR1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.966927 View
ENSG00000091831 ESR1 ENSG00000157540 DYRK1A H. sapiens SDL Slorth 0.966923 View
ENSG00000091831 ESR1 ENSG00000197122 SRC H. sapiens SDL Slorth 0.966889 View
ENSG00000091831 ESR1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.966828 View
ENSG00000037042 TUBG2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966802 View
ENSG00000091831 ESR1 ENSG00000101421 CHMP4B H. sapiens SDL Slorth 0.966795 View
ENSG00000091831 ESR1 ENSG00000138107 ACTR1A H. sapiens SDL Slorth 0.966795 View
ENSG00000091831 ESR1 ENSG00000101665 SMAD7 H. sapiens SDL Slorth 0.966757 View
ENSG00000091831 ESR1 ENSG00000162909 CAPN2 H. sapiens SDL Slorth 0.966754 View
ENSG00000078399 HOXA9 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966751 View
ENSG00000081721 DUSP12 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966747 View
ENSG00000006451 RALA ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966727 View
ENSG00000066056 TIE1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966724 View
ENSG00000008128 CDK11A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966699 View
ENSG00000075426 FOSL2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966687 View
ENSG00000091831 ESR1 ENSG00000111300 NAA25 H. sapiens SDL Slorth 0.966672 View
ENSG00000091831 ESR1 ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.966639 View
ENSG00000091831 ESR1 ENSG00000121653 MAPK8IP1 H. sapiens SDL Slorth 0.966582 View
ENSG00000091831 ESR1 ENSG00000175203 DCTN2 H. sapiens SDL Slorth 0.966542 View
ENSG00000091831 ESR1 ENSG00000117984 CTSD H. sapiens SDL Slorth 0.966522 View
ENSG00000091831 ESR1 ENSG00000164116 GUCY1A3 H. sapiens SDL Slorth 0.966521 View
ENSG00000091831 ESR1 ENSG00000143473 KCNH1 H. sapiens SDL Slorth 0.966462 View
ENSG00000091831 ESR1 ENSG00000103275 UBE2I H. sapiens SDL Slorth 0.96646 View
ENSG00000091831 ESR1 ENSG00000151694 ADAM17 H. sapiens SDL Slorth 0.966438 View
ENSG00000091831 ESR1 ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.966438 View
ENSG00000064489 BORCS8-MEF2B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966435 View
ENSG00000091831 ESR1 ENSG00000140990 NDUFB10 H. sapiens SDL Slorth 0.966434 View
ENSG00000091831 ESR1 ENSG00000196923 PDLIM7 H. sapiens SDL Slorth 0.966415 View
ENSG00000091831 ESR1 ENSG00000103342 GSPT1 H. sapiens SDL Slorth 0.966371 View
ENSG00000083642 PDS5B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966332 View
ENSG00000039068 CDH1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966299 View
ENSG00000067057 PFKP ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.966137 View