ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000178035 IMPDH2 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000144746 ARL6IP5 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000157954 WIPI2 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000131238 PPT1 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000100836 PABPN1 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000132141 CCT6B H. sapiens SDL Slorth 0.969186 View
ENSG00000091831 ESR1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.96918 View
ENSG00000091831 ESR1 ENSG00000100412 ACO2 H. sapiens SDL Slorth 0.969167 View
ENSG00000049618 ARID1B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969147 View
ENSG00000079950 STX7 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969128 View
ENSG00000010017 RANBP9 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969115 View
ENSG00000091831 ESR1 ENSG00000127663 KDM4B H. sapiens SDL Slorth 0.969105 View
ENSG00000091831 ESR1 ENSG00000163349 HIPK1 H. sapiens SDL Slorth 0.969105 View
ENSG00000066135 KDM4A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969035 View
ENSG00000091831 ESR1 ENSG00000173327 MAP3K11 H. sapiens SDL Slorth 0.96902 View
ENSG00000091831 ESR1 ENSG00000125354 SEPT6 H. sapiens SDL Slorth 0.968993 View
ENSG00000091831 ESR1 ENSG00000154767 XPC H. sapiens SDL Slorth 0.968989 View
ENSG00000072110 ACTN1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968985 View
ENSG00000091831 ESR1 ENSG00000213024 NUP62 H. sapiens SDL Slorth 0.968982 View
ENSG00000091831 ESR1 ENSG00000173933 RBM4 H. sapiens SDL Slorth 0.968977 View
ENSG00000091831 ESR1 ENSG00000159210 SNF8 H. sapiens SDL Slorth 0.968923 View
ENSG00000091831 ESR1 ENSG00000169189 NSMCE1 H. sapiens SDL Slorth 0.968883 View
ENSG00000091831 ESR1 ENSG00000239306 RBM14 H. sapiens SDL Slorth 0.968882 View
ENSG00000089159 PXN ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968846 View
ENSG00000087095 NLK ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968784 View
ENSG00000082781 ITGB5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968702 View
ENSG00000091831 ESR1 ENSG00000172671 ZFAND4 H. sapiens SDL Slorth 0.968697 View
ENSG00000091831 ESR1 ENSG00000126803 HSPA2 H. sapiens SDL Slorth 0.968691 View
ENSG00000091831 ESR1 ENSG00000121022 COPS5 H. sapiens SDL Slorth 0.968675 View
ENSG00000091831 ESR1 ENSG00000149554 CHEK1 H. sapiens SDL Slorth 0.968642 View
ENSG00000091831 ESR1 ENSG00000130479 MAP1S H. sapiens SDL Slorth 0.968517 View
ENSG00000080839 RBL1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.96846 View
ENSG00000091831 ESR1 ENSG00000115282 TTC31 H. sapiens SDL Slorth 0.968447 View
ENSG00000091831 ESR1 ENSG00000106462 EZH2 H. sapiens SDL Slorth 0.968399 View
ENSG00000091831 ESR1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.968394 View
ENSG00000091831 ESR1 ENSG00000179218 CALR H. sapiens SDL Slorth 0.968334 View
ENSG00000091831 ESR1 ENSG00000177613 CSTF2T H. sapiens SDL Slorth 0.968268 View
ENSG00000048540 LMO3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.968247 View
ENSG00000091831 ESR1 ENSG00000173812 EIF1 H. sapiens SDL Slorth 0.968235 View
ENSG00000091831 ESR1 ENSG00000160285 LSS H. sapiens SDL Slorth 0.968219 View