MSH6

ENSG00000116062 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0030983 mismatched DNA binding
GO:0035064 methylated histone binding
GO:0042803 protein homodimerization activity
GO:0000287 magnesium ion binding
GO:0000400 four-way junction DNA binding
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0032137 guanine/thymine mispair binding
GO:0032142 single guanine insertion binding
GO:0032143 single thymine insertion binding
GO:0032357 oxidized purine DNA binding
GO:0032405 MutLalpha complex binding
GO:0043531 ADP binding
GO:0003677 DNA binding
GO:0000166 nucleotide binding
GO:0032138 single base insertion or deletion binding
GO:0003684 damaged DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
endometrial
ovarian

Orthologs

Gene Organism
MSH6 S. cerevisiae
msh-6 C. elegans
Msh6 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000147050 KDM6A ENSG00000116062 MSH6 H. sapiens SSL BioGRID 1.0 View
ENSG00000012048 BRCA1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.993483 View
ENSG00000100393 EP300 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.987214 View
ENSG00000005339 CREBBP ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.986948 View
ENSG00000116062 MSH6 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.985544 View
ENSG00000116062 MSH6 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.984913 View
ENSG00000116062 MSH6 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.982329 View
ENSG00000116062 MSH6 ENSG00000170315 UBB H. sapiens SDL Slorth 0.979486 View
ENSG00000116062 MSH6 ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.978857 View
ENSG00000116062 MSH6 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.978702 View
ENSG00000041357 PSMA4 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.977113 View
ENSG00000100030 MAPK1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.976899 View
ENSG00000116062 MSH6 ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.97612 View
ENSG00000100906 NFKBIA ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.976011 View
ENSG00000116062 MSH6 ENSG00000136997 MYC H. sapiens SDL Slorth 0.975811 View
ENSG00000101266 CSNK2A1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.975781 View
ENSG00000080824 HSP90AA1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.975538 View
ENSG00000116062 MSH6 ENSG00000150991 UBC H. sapiens SDL Slorth 0.974681 View
ENSG00000109670 FBXW7 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.973654 View
ENSG00000116062 MSH6 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.972485 View
ENSG00000116030 SUMO1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.971356 View
ENSG00000101266 CSNK2A1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.969891 View
ENSG00000091831 ESR1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.96918 View
ENSG00000110395 CBL ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.968651 View
ENSG00000103275 UBE2I ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.9684 View
ENSG00000082701 GSK3B ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.968245 View
ENSG00000103275 UBE2I ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.967242 View
ENSG00000100644 HIF1A ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.967233 View
ENSG00000005339 CREBBP ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.967175 View
ENSG00000012048 BRCA1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.967151 View
ENSG00000116062 MSH6 ENSG00000177606 JUN H. sapiens SDL Slorth 0.965434 View
ENSG00000112592 TBP ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.965152 View
ENSG00000116062 MSH6 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.964562 View
ENSG00000100030 MAPK1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.964493 View
ENSG00000116062 MSH6 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.964448 View
ENSG00000110395 CBL ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.964415 View
ENSG00000116062 MSH6 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.964386 View
ENSG00000072401 UBE2D1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.963963 View
ENSG00000116062 MSH6 ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.962969 View
ENSG00000116062 MSH6 ENSG00000169083 AR H. sapiens SDL Slorth 0.962591 View