MSH6

ENSG00000116062 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0030983 mismatched DNA binding
GO:0035064 methylated histone binding
GO:0042803 protein homodimerization activity
GO:0000287 magnesium ion binding
GO:0000400 four-way junction DNA binding
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0032137 guanine/thymine mispair binding
GO:0032142 single guanine insertion binding
GO:0032143 single thymine insertion binding
GO:0032357 oxidized purine DNA binding
GO:0032405 MutLalpha complex binding
GO:0043531 ADP binding
GO:0003677 DNA binding
GO:0000166 nucleotide binding
GO:0032138 single base insertion or deletion binding
GO:0003684 damaged DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
endometrial
ovarian

Orthologs

Gene Organism
MSH6 S. cerevisiae
msh-6 C. elegans
Msh6 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000082701 GSK3B ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.913919 View
ENSG00000113575 PPP2CA ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.913129 View
ENSG00000116062 MSH6 ENSG00000197299 BLM H. sapiens SDL Slorth 0.913013 View
ENSG00000106588 PSMA2 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.912942 View
ENSG00000114391 RPL24 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.912774 View
ENSG00000100387 RBX1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.912046 View
ENSG00000103194 USP10 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.911996 View
ENSG00000116062 MSH6 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.911932 View
ENSG00000110107 PRPF19 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.911885 View
ENSG00000116062 MSH6 ENSG00000154767 XPC H. sapiens SDL Slorth 0.911719 View
ENSG00000094804 CDC6 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.911486 View
ENSG00000001626 CFTR ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.911248 View
ENSG00000078747 ITCH ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.910735 View
ENSG00000070950 RAD18 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.909926 View
ENSG00000100138 SNU13 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.909768 View
ENSG00000108424 KPNB1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.909722 View
ENSG00000114166 KAT2B ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.90971 View
ENSG00000101843 PSMD10 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.909185 View
ENSG00000070010 UFD1L ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.908803 View
ENSG00000109670 FBXW7 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.908522 View
ENSG00000108671 PSMD11 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.908434 View
ENSG00000049759 NEDD4L ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.90779 View
ENSG00000101868 POLA1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.907528 View
ENSG00000004700 RECQL ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.907246 View
ENSG00000116062 MSH6 ENSG00000168028 RPSA H. sapiens SDL Slorth 0.907107 View
ENSG00000087191 PSMC5 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.906948 View
ENSG00000102882 MAPK3 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.90651 View
ENSG00000116062 MSH6 ENSG00000161057 PSMC2 H. sapiens SDL Slorth 0.905915 View
ENSG00000096968 JAK2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.905872 View
ENSG00000064012 CASP8 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.904252 View
ENSG00000074201 CLNS1A ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.903808 View
ENSG00000070831 CDC42 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.903485 View
ENSG00000080824 HSP90AA1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.903346 View
ENSG00000110713 NUP98 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.903243 View
ENSG00000105974 CAV1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.903096 View
ENSG00000114062 UBE3A ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.902843 View
ENSG00000069869 NEDD4 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.90274 View
ENSG00000099956 SMARCB1 ENSG00000116062 MSH6 H. sapiens SDL Slorth 0.9012 View
ENSG00000095002 MSH2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.900624 View
ENSG00000005007 UPF1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.899972 View