CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.983014 View
ENSG00000001626 CFTR ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.982992 View
ENSG00000001626 CFTR ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.981836 View
ENSG00000001626 CFTR ENSG00000049323 LTBP1 H. sapiens SDL Slorth 0.980373 View
ENSG00000001626 CFTR ENSG00000143420 ENSA H. sapiens SDL Slorth 0.980148 View
ENSG00000001626 CFTR ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.979968 View
ENSG00000001626 CFTR ENSG00000150991 UBC H. sapiens SDL Slorth 0.979642 View
ENSG00000001626 CFTR ENSG00000120539 MASTL H. sapiens SDL Slorth 0.979631 View
ENSG00000001626 CFTR ENSG00000100968 NFATC4 H. sapiens SDL Slorth 0.979398 View
ENSG00000001626 CFTR ENSG00000135723 FHOD1 H. sapiens SDL Slorth 0.979394 View
ENSG00000001626 CFTR ENSG00000137825 ITPKA H. sapiens SDL Slorth 0.979282 View
ENSG00000001626 CFTR ENSG00000160145 KALRN H. sapiens SDL Slorth 0.979098 View
ENSG00000001626 CFTR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979081 View
ENSG00000001626 CFTR ENSG00000189067 LITAF H. sapiens SDL Slorth 0.978883 View
ENSG00000001626 CFTR ENSG00000107929 LARP4B H. sapiens SDL Slorth 0.978649 View
ENSG00000001626 CFTR ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.978634 View
ENSG00000001626 CFTR ENSG00000100320 RBFOX2 H. sapiens SDL Slorth 0.97857 View
ENSG00000001626 CFTR ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.978361 View
ENSG00000001626 CFTR ENSG00000100092 SH3BP1 H. sapiens SDL Slorth 0.978254 View
ENSG00000001626 CFTR ENSG00000157601 MX1 H. sapiens SDL Slorth 0.978216 View
ENSG00000001626 CFTR ENSG00000165409 TSHR H. sapiens SDL Slorth 0.978148 View
ENSG00000001626 CFTR ENSG00000130766 SESN2 H. sapiens SDL Slorth 0.977488 View
ENSG00000001626 CFTR ENSG00000126368 NR1D1 H. sapiens SDL Slorth 0.97731 View
ENSG00000001626 CFTR ENSG00000073614 KDM5A H. sapiens SDL Slorth 0.977287 View
ENSG00000001626 CFTR ENSG00000184937 WT1 H. sapiens SDL Slorth 0.977111 View
ENSG00000001626 CFTR ENSG00000015285 WAS H. sapiens SDL Slorth 0.977024 View
ENSG00000001626 CFTR ENSG00000107036 RIC1 H. sapiens SDL Slorth 0.976721 View
ENSG00000001626 CFTR ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.976471 View
ENSG00000001626 CFTR ENSG00000144668 ITGA9 H. sapiens SDL Slorth 0.976336 View
ENSG00000001626 CFTR ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.97599 View
ENSG00000001626 CFTR ENSG00000104892 KLC3 H. sapiens SDL Slorth 0.975989 View
ENSG00000001626 CFTR ENSG00000115221 ITGB6 H. sapiens SDL Slorth 0.975561 View
ENSG00000001626 CFTR ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.974814 View
ENSG00000001626 CFTR ENSG00000151692 RNF144A H. sapiens SDL Slorth 0.974723 View
ENSG00000001626 CFTR ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.974702 View
ENSG00000001626 CFTR ENSG00000163098 BIRC8 H. sapiens SDL Slorth 0.974192 View
ENSG00000001626 CFTR ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.974144 View
ENSG00000001626 CFTR ENSG00000070778 PTPN21 H. sapiens SDL Slorth 0.974136 View
ENSG00000001626 CFTR ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.974082 View
ENSG00000001626 CFTR ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.974079 View