CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.957843 View
ENSG00000001626 CFTR ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.957527 View
ENSG00000001626 CFTR ENSG00000004897 CDC27 H. sapiens SSL Slorth 0.957453 View
ENSG00000001626 CFTR ENSG00000116044 NFE2L2 H. sapiens SSL Slorth 0.957429 View
ENSG00000001626 CFTR ENSG00000132170 PPARG H. sapiens SSL Slorth 0.957423 View
ENSG00000001626 CFTR ENSG00000137693 YAP1 H. sapiens SSL Slorth 0.957403 View
ENSG00000001626 CFTR ENSG00000117676 RPS6KA1 H. sapiens SSL Slorth 0.957351 View
ENSG00000001626 CFTR ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.957335 View
ENSG00000001626 CFTR ENSG00000185359 HGS H. sapiens SSL Slorth 0.956981 View
ENSG00000001626 CFTR ENSG00000104365 IKBKB H. sapiens SSL Slorth 0.95688 View
ENSG00000001626 CFTR ENSG00000157106 SMG1 H. sapiens SSL Slorth 0.956744 View
ENSG00000001626 CFTR ENSG00000134308 YWHAQ H. sapiens SSL Slorth 0.956666 View
ENSG00000001626 CFTR ENSG00000105976 MET H. sapiens SSL Slorth 0.95657 View
ENSG00000001626 CFTR ENSG00000105810 CDK6 H. sapiens SSL Slorth 0.956553 View
ENSG00000001626 CFTR ENSG00000072310 SREBF1 H. sapiens SSL Slorth 0.956496 View
ENSG00000001626 CFTR ENSG00000132341 RAN H. sapiens SSL Slorth 0.956463 View
ENSG00000001626 CFTR ENSG00000122966 CIT H. sapiens SDL Slorth 0.956245 View
ENSG00000001626 CFTR ENSG00000149930 TAOK2 H. sapiens SDL Slorth 0.956161 View
ENSG00000001626 CFTR ENSG00000167552 TUBA1A H. sapiens SDL Slorth 0.955981 View
ENSG00000001626 CFTR ENSG00000128052 KDR H. sapiens SSL Slorth 0.955951 View
ENSG00000001626 CFTR ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.955903 View
ENSG00000001626 CFTR ENSG00000131941 RHPN2 H. sapiens SDL Slorth 0.955858 View
ENSG00000001626 CFTR ENSG00000167461 RAB8A H. sapiens SDL Slorth 0.955801 View
ENSG00000001626 CFTR ENSG00000165731 RET H. sapiens SSL Slorth 0.955582 View
ENSG00000001626 CFTR ENSG00000108443 RPS6KB1 H. sapiens SSL Slorth 0.955575 View
ENSG00000001626 CFTR ENSG00000213923 CSNK1E H. sapiens SSL Slorth 0.955423 View
ENSG00000001626 CFTR ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.955261 View
ENSG00000001626 CFTR ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.955261 View
ENSG00000001626 CFTR ENSG00000108883 EFTUD2 H. sapiens SSL Slorth 0.955006 View
ENSG00000001626 CFTR ENSG00000074319 TSG101 H. sapiens SSL Slorth 0.954941 View
ENSG00000001626 CFTR ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.954366 View
ENSG00000001626 CFTR ENSG00000100028 SNRPD3 H. sapiens SSL Slorth 0.954254 View
ENSG00000001626 CFTR ENSG00000136237 RAPGEF5 H. sapiens SDL Slorth 0.954202 View
ENSG00000001626 CFTR ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.954199 View
ENSG00000001626 CFTR ENSG00000135486 HNRNPA1 H. sapiens SSL Slorth 0.953984 View
ENSG00000001626 CFTR ENSG00000106211 HSPB1 H. sapiens SSL Slorth 0.953712 View
ENSG00000001626 CFTR ENSG00000103197 TSC2 H. sapiens SSL Slorth 0.953494 View
ENSG00000001626 CFTR ENSG00000165416 SUGT1 H. sapiens SSL Slorth 0.95333 View
ENSG00000001626 CFTR ENSG00000118689 FOXO3 H. sapiens SSL Slorth 0.95331 View
ENSG00000001626 CFTR ENSG00000169252 ADRB2 H. sapiens SDL Slorth 0.953233 View