CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000123094 RASSF8 H. sapiens SDL Slorth 0.965085 View
ENSG00000001626 CFTR ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.965036 View
ENSG00000001626 CFTR ENSG00000078747 ITCH H. sapiens SSL Slorth 0.964879 View
ENSG00000001626 CFTR ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.964832 View
ENSG00000001626 CFTR ENSG00000007908 SELE H. sapiens SDL Slorth 0.964805 View
ENSG00000001626 CFTR ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.964717 View
ENSG00000001626 CFTR ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.96463 View
ENSG00000001626 CFTR ENSG00000146094 DOK3 H. sapiens SDL Slorth 0.964607 View
ENSG00000001626 CFTR ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.964583 View
ENSG00000001626 CFTR ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.964555 View
ENSG00000001626 CFTR ENSG00000012048 BRCA1 H. sapiens SDL Slorth 0.964498 View
ENSG00000001626 CFTR ENSG00000128512 DOCK4 H. sapiens SDL Slorth 0.964393 View
ENSG00000001626 CFTR ENSG00000124486 USP9X H. sapiens SSL Slorth 0.964243 View
ENSG00000001626 CFTR ENSG00000114062 UBE3A H. sapiens SSL Slorth 0.96415 View
ENSG00000001626 CFTR ENSG00000039068 CDH1 H. sapiens SSL Slorth 0.963976 View
ENSG00000001626 CFTR ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.963969 View
ENSG00000001626 CFTR ENSG00000005007 UPF1 H. sapiens SSL Slorth 0.963911 View
ENSG00000001626 CFTR ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.963792 View
ENSG00000001626 CFTR ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.963783 View
ENSG00000001626 CFTR ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.963602 View
ENSG00000001626 CFTR ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.963568 View
ENSG00000001626 CFTR ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.963464 View
ENSG00000001626 CFTR ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.963222 View
ENSG00000001626 CFTR ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.9631 View
ENSG00000001626 CFTR ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.963077 View
ENSG00000001626 CFTR ENSG00000170315 UBB H. sapiens SDL Slorth 0.963031 View
ENSG00000001626 CFTR ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.962959 View
ENSG00000001626 CFTR ENSG00000108953 YWHAE H. sapiens SSL Slorth 0.962863 View
ENSG00000001626 CFTR ENSG00000140464 PML H. sapiens SSL Slorth 0.962677 View
ENSG00000001626 CFTR ENSG00000072062 PRKACA H. sapiens SSL Slorth 0.962676 View
ENSG00000001626 CFTR ENSG00000114503 NCBP2 H. sapiens SSL Slorth 0.962667 View
ENSG00000001626 CFTR ENSG00000170027 YWHAG H. sapiens SSL Slorth 0.96265 View
ENSG00000001626 CFTR ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.962616 View
ENSG00000001626 CFTR ENSG00000175766 EIF4E1B H. sapiens SDL Slorth 0.962383 View
ENSG00000001626 CFTR ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.962186 View
ENSG00000001626 CFTR ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.962167 View
ENSG00000001626 CFTR ENSG00000110330 BIRC2 H. sapiens SSL Slorth 0.962132 View
ENSG00000001626 CFTR ENSG00000061938 TNK2 H. sapiens SSL Slorth 0.962087 View
ENSG00000001626 CFTR ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.961968 View
ENSG00000001626 CFTR ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.961885 View