CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000109572 CLCN3 H. sapiens SDL Slorth 0.949604 View
ENSG00000001626 CFTR ENSG00000170345 FOS H. sapiens SSL Slorth 0.94956 View
ENSG00000001626 CFTR ENSG00000123374 CDK2 H. sapiens SSL Slorth 0.949546 View
ENSG00000001626 CFTR ENSG00000186716 BCR H. sapiens SSL Slorth 0.94953 View
ENSG00000001626 CFTR ENSG00000150907 FOXO1 H. sapiens SSL Slorth 0.949435 View
ENSG00000001626 CFTR ENSG00000147010 SH3KBP1 H. sapiens SDL Slorth 0.949365 View
ENSG00000001626 CFTR ENSG00000010810 FYN H. sapiens SSL Slorth 0.949329 View
ENSG00000001626 CFTR ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.949269 View
ENSG00000001626 CFTR ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.949263 View
ENSG00000001626 CFTR ENSG00000100387 RBX1 H. sapiens SSL Slorth 0.949213 View
ENSG00000001626 CFTR ENSG00000085832 EPS15 H. sapiens SSL Slorth 0.949143 View
ENSG00000001626 CFTR ENSG00000146648 EGFR H. sapiens SDL Slorth 0.949022 View
ENSG00000001626 CFTR ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.948971 View
ENSG00000001626 CFTR ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.948949 View
ENSG00000001626 CFTR ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.948949 View
ENSG00000001626 CFTR ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.948596 View
ENSG00000001626 CFTR ENSG00000168610 STAT3 H. sapiens SSL Slorth 0.948578 View
ENSG00000001626 CFTR ENSG00000169083 AR H. sapiens SDL Slorth 0.948498 View
ENSG00000001626 CFTR ENSG00000131747 TOP2A H. sapiens SSL Slorth 0.948442 View
ENSG00000001626 CFTR ENSG00000136937 NCBP1 H. sapiens SSL Slorth 0.948259 View
ENSG00000001626 CFTR ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.948146 View
ENSG00000001626 CFTR ENSG00000069399 BCL3 H. sapiens SSL Slorth 0.948121 View
ENSG00000001626 CFTR ENSG00000283094 PTEN H. sapiens SSL Slorth 0.948063 View
ENSG00000001626 CFTR ENSG00000176720 BOK H. sapiens SDL Slorth 0.947938 View
ENSG00000001626 CFTR ENSG00000134086 VHL H. sapiens SSL Slorth 0.947896 View
ENSG00000001626 CFTR ENSG00000187555 USP7 H. sapiens SSL Slorth 0.947817 View
ENSG00000001626 CFTR ENSG00000109971 HSPA8 H. sapiens SSL Slorth 0.947773 View
ENSG00000001626 CFTR ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.947603 View
ENSG00000001626 CFTR ENSG00000114030 KPNA1 H. sapiens SSL Slorth 0.947442 View
ENSG00000001626 CFTR ENSG00000145907 G3BP1 H. sapiens SDL Slorth 0.947343 View
ENSG00000001626 CFTR ENSG00000065054 SLC9A3R2 H. sapiens SDL Slorth 0.947314 View
ENSG00000001626 CFTR ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.947071 View
ENSG00000001626 CFTR ENSG00000044115 CTNNA1 H. sapiens SSL Slorth 0.947059 View
ENSG00000001626 CFTR ENSG00000104695 PPP2CB H. sapiens SSL Slorth 0.946904 View
ENSG00000001626 CFTR ENSG00000166598 HSP90B1 H. sapiens SSL Slorth 0.946852 View
ENSG00000001626 CFTR ENSG00000198561 CTNND1 H. sapiens SSL Slorth 0.94672 View
ENSG00000001626 CFTR ENSG00000130939 UBE4B H. sapiens SSL Slorth 0.946439 View
ENSG00000001626 CFTR ENSG00000101266 CSNK2A1 H. sapiens SSL Slorth 0.946337 View
ENSG00000001626 CFTR ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.945991 View
ENSG00000001626 CFTR ENSG00000128245 YWHAH H. sapiens SSL Slorth 0.9459 View