HDAC1

ENSG00000116478 - H. sapiens

Pathways

Go term Description
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0001047 core promoter binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0001103 RNA polymerase II repressing transcription factor binding
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558 protein deacetylase activity
GO:0033613 activating transcription factor binding
GO:0042826 histone deacetylase binding
GO:0044212 transcription regulatory region DNA binding
GO:0047485 protein N-terminus binding
GO:0051059 NF-kappaB binding
GO:0070491 repressing transcription factor binding
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0031492 nucleosomal DNA binding

Drugs

Drug name Description
BELINOSTAT Histone deacetylase inhibitor
PANOBINOSTAT Histone deacetylase inhibitor
ROMIDEPSIN Histone deacetylase inhibitor
VORINOSTAT Histone deacetylase 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
RPD3 S. cerevisiae
hda-1 C. elegans
hda-3 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113812 ACTR8 ENSG00000116478 HDAC1 H. sapiens SSL BioGRID 1.0 View
ENSG00000135446 CDK4 ENSG00000116478 HDAC1 H. sapiens SSL BioGRID 1.0 View
ENSG00000116478 HDAC1 ENSG00000159479 MED8 H. sapiens SSL BioGRID 1.0 View
ENSG00000116478 HDAC1 ENSG00000100462 PRMT5 H. sapiens SSL BioGRID 1.0 View
ENSG00000116478 HDAC1 ENSG00000153147 SMARCA5 H. sapiens SDL Slorth 0.991518 View
ENSG00000116478 HDAC1 ENSG00000178691 SUZ12 H. sapiens SDL Slorth 0.991118 View
ENSG00000116478 HDAC1 ENSG00000117751 PPP1R8 H. sapiens SDL Slorth 0.990562 View
ENSG00000116478 HDAC1 ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.990458 View
ENSG00000116478 HDAC1 ENSG00000140299 BNIP2 H. sapiens SDL Slorth 0.990294 View
ENSG00000116478 HDAC1 ENSG00000124216 SNAI1 H. sapiens SDL Slorth 0.990268 View
ENSG00000116478 HDAC1 ENSG00000131773 KHDRBS3 H. sapiens SDL Slorth 0.990254 View
ENSG00000116478 HDAC1 ENSG00000140538 NTRK3 H. sapiens SDL Slorth 0.990103 View
ENSG00000116478 HDAC1 ENSG00000178562 CD28 H. sapiens SDL Slorth 0.990076 View
ENSG00000116478 HDAC1 ENSG00000155974 GRIP1 H. sapiens SDL Slorth 0.990071 View
ENSG00000116478 HDAC1 ENSG00000122779 TRIM24 H. sapiens SDL Slorth 0.990035 View
ENSG00000116478 HDAC1 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.989941 View
ENSG00000116478 HDAC1 ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.989941 View
ENSG00000116478 HDAC1 ENSG00000134070 IRAK2 H. sapiens SDL Slorth 0.989873 View
ENSG00000116478 HDAC1 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.989688 View
ENSG00000116478 HDAC1 ENSG00000140807 NKD1 H. sapiens SDL Slorth 0.98959 View
ENSG00000116478 HDAC1 ENSG00000171094 ALK H. sapiens SDL Slorth 0.989419 View
ENSG00000116478 HDAC1 ENSG00000135605 TEC H. sapiens SDL Slorth 0.989394 View
ENSG00000116478 HDAC1 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.989294 View
ENSG00000116478 HDAC1 ENSG00000178188 SH2B1 H. sapiens SDL Slorth 0.989272 View
ENSG00000116478 HDAC1 ENSG00000153201 RANBP2 H. sapiens SDL Slorth 0.989241 View
ENSG00000116478 HDAC1 ENSG00000174738 NR1D2 H. sapiens SDL Slorth 0.989217 View
ENSG00000116478 HDAC1 ENSG00000143379 SETDB1 H. sapiens SDL Slorth 0.9892 View
ENSG00000116478 HDAC1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.989114 View
ENSG00000116478 HDAC1 ENSG00000198900 TOP1 H. sapiens SDL Slorth 0.989024 View
ENSG00000116478 HDAC1 ENSG00000163904 SENP2 H. sapiens SDL Slorth 0.989024 View
ENSG00000116478 HDAC1 ENSG00000173801 JUP H. sapiens SDL Slorth 0.989008 View
ENSG00000116478 HDAC1 ENSG00000163602 RYBP H. sapiens SDL Slorth 0.988871 View
ENSG00000116478 HDAC1 ENSG00000183814 LIN9 H. sapiens SDL Slorth 0.988845 View
ENSG00000116478 HDAC1 ENSG00000156475 PPP2R2B H. sapiens SDL Slorth 0.98884 View
ENSG00000116478 HDAC1 ENSG00000130382 MLLT1 H. sapiens SDL Slorth 0.988786 View
ENSG00000116478 HDAC1 ENSG00000198001 IRAK4 H. sapiens SDL Slorth 0.988759 View
ENSG00000116478 HDAC1 ENSG00000120833 SOCS2 H. sapiens SDL Slorth 0.988669 View
ENSG00000116478 HDAC1 ENSG00000147443 DOK2 H. sapiens SDL Slorth 0.988645 View
ENSG00000116478 HDAC1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.988604 View
ENSG00000116478 HDAC1 ENSG00000198901 PRC1 H. sapiens SDL Slorth 0.988586 View