PTEN

ENSG00000283094 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0004438 phosphatidylinositol-3-phosphatase activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0008289 lipid binding
GO:0010997 anaphase-promoting complex binding
GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030165 PDZ domain binding
GO:0042802 identical protein binding
GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0003779 actin binding

Drugs

No drugs in record

Diseases

Disease Name
glioma
prostate
endometrial
harmartoma

Orthologs

Gene Organism
daf-18 C. elegans
Pten D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000283094 PTEN ENSG00000108774 RAB5C H. sapiens SSL BioGRID 1.0 View
ENSG00000283094 PTEN ENSG00000138802 SEC24B H. sapiens SSL BioGRID 1.0 View
ENSG00000283094 PTEN ENSG00000113597 TRAPPC13 H. sapiens SSL BioGRID 1.0 View
ENSG00000283094 PTEN ENSG00000134086 VHL H. sapiens SSL BioGRID 1.0 View
ENSG00000283094 PTEN ENSG00000141252 VPS53 H. sapiens SSL BioGRID 1.0 View
ENSG00000170340 B3GNT2 ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000141867 BRD4 ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000111530 CAND1 ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000149554 CHEK1 ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000074266 EED ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000159217 IGF2BP1 ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000088247 KHSRP ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000177239 MAN1B1 ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000198793 MTOR ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000100393 EP300 ENSG00000283094 PTEN H. sapiens SDL Slorth 0.990337 View
ENSG00000005339 CREBBP ENSG00000283094 PTEN H. sapiens SDL Slorth 0.988217 View
ENSG00000132646 PCNA ENSG00000283094 PTEN H. sapiens SDL Slorth 0.982826 View
ENSG00000150991 UBC ENSG00000283094 PTEN H. sapiens SDL Slorth 0.979275 View
ENSG00000162385 MAGOH ENSG00000283094 PTEN H. sapiens SDL Slorth 0.978966 View
ENSG00000124762 CDKN1A ENSG00000283094 PTEN H. sapiens SDL Slorth 0.978635 View
ENSG00000139687 RB1 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.977238 View
ENSG00000121022 COPS5 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.97707 View
ENSG00000101266 CSNK2A1 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.976758 View
ENSG00000166167 BTRC ENSG00000283094 PTEN H. sapiens SSL Slorth 0.975758 View
ENSG00000012048 BRCA1 ENSG00000283094 PTEN H. sapiens SDL Slorth 0.975614 View
ENSG00000170315 UBB ENSG00000283094 PTEN H. sapiens SDL Slorth 0.97544 View
ENSG00000005339 CREBBP ENSG00000283094 PTEN H. sapiens SSL Slorth 0.97543 View
ENSG00000101412 E2F1 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.975281 View
ENSG00000139687 RB1 ENSG00000283094 PTEN H. sapiens SDL Slorth 0.974947 View
ENSG00000136997 MYC ENSG00000283094 PTEN H. sapiens SSL Slorth 0.974788 View
ENSG00000141510 TP53 ENSG00000283094 PTEN H. sapiens SDL Slorth 0.974364 View
ENSG00000080824 HSP90AA1 ENSG00000283094 PTEN H. sapiens SDL Slorth 0.974295 View
ENSG00000283094 PTEN ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.974079 View
ENSG00000132383 RPA1 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.973709 View
ENSG00000160691 SHC1 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.97363 View
ENSG00000133703 KRAS ENSG00000283094 PTEN H. sapiens SSL Slorth 0.973473 View
ENSG00000123374 CDK2 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.973097 View
ENSG00000171791 BCL2 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.972755 View
ENSG00000169375 SIN3A ENSG00000283094 PTEN H. sapiens SSL Slorth 0.972685 View