|
Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
|
KRAS
|
ENSG00000133703
|
pancreatic
colorectal
lung
thyroid
AML
other tumour types
|
No drugs in record
|
GTPase activity
protein binding
GTP binding
GMP binding
GDP binding
LRR domain binding
protein complex binding
|
RAS1 (S. cerevisiae)
RAS2 (S. cerevisiae)
let-60 (C. elegans)
Ras85D (D. melanogaster)
|
|
PTEN
|
ENSG00000283094
|
glioma
prostate
endometrial
harmartoma
|
No drugs in record
|
magnesium ion binding
phosphatidylinositol-3-phosphatase activity
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
platelet-derived growth factor receptor binding
protein binding
protein tyrosine/serine/threonine phosphatase activity
lipid binding
anaphase-promoting complex binding
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
enzyme binding
protein kinase binding
PDZ domain binding
identical protein binding
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
actin binding
|
daf-18 (C. elegans)
Pten (D. melanogaster)
|
