BRCA1 - PTEN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRCA1	ENSG00000012048	ovarian breast	No drugs in record	DNA binding damaged DNA binding transcription coactivator activity RNA binding ubiquitin-protein transferase activity protein binding zinc ion binding tubulin binding enzyme binding ubiquitin protein ligase binding transcription regulatory region DNA binding androgen receptor binding	No GO terms in record
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)