SHC1 - PTEN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SHC1	ENSG00000160691	No diseases in record	No drugs in record	transmembrane receptor protein tyrosine kinase adaptor activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding insulin receptor binding insulin-like growth factor receptor binding neurotrophin TRKA receptor binding protein binding phospholipid binding ephrin receptor binding epidermal growth factor binding enzyme activator activity	No GO terms in record
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)