CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000131400 NAPSA H. sapiens SDL Slorth 0.968676 View
ENSG00000001626 CFTR ENSG00000082898 XPO1 H. sapiens SSL Slorth 0.968652 View
ENSG00000001626 CFTR ENSG00000141510 TP53 H. sapiens SDL Slorth 0.968455 View
ENSG00000001626 CFTR ENSG00000159496 RGL4 H. sapiens SDL Slorth 0.968429 View
ENSG00000001626 CFTR ENSG00000135597 REPS1 H. sapiens SDL Slorth 0.968306 View
ENSG00000001626 CFTR ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.968088 View
ENSG00000001626 CFTR ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.968088 View
ENSG00000001626 CFTR ENSG00000081059 TCF7 H. sapiens SDL Slorth 0.968088 View
ENSG00000001626 CFTR ENSG00000072163 LIMS2 H. sapiens SDL Slorth 0.96798 View
ENSG00000001626 CFTR ENSG00000101134 DOK5 H. sapiens SDL Slorth 0.967873 View
ENSG00000001626 CFTR ENSG00000119866 BCL11A H. sapiens SDL Slorth 0.967823 View
ENSG00000001626 CFTR ENSG00000101665 SMAD7 H. sapiens SSL Slorth 0.967795 View
ENSG00000001626 CFTR ENSG00000143776 CDC42BPA H. sapiens SDL Slorth 0.967606 View
ENSG00000001626 CFTR ENSG00000182511 FES H. sapiens SDL Slorth 0.9676 View
ENSG00000001626 CFTR ENSG00000129204 USP6 H. sapiens SDL Slorth 0.9675 View
ENSG00000001626 CFTR ENSG00000109332 UBE2D3 H. sapiens SSL Slorth 0.967447 View
ENSG00000001626 CFTR ENSG00000132005 RFX1 H. sapiens SDL Slorth 0.967413 View
ENSG00000001626 CFTR ENSG00000111218 PRMT8 H. sapiens SDL Slorth 0.967114 View
ENSG00000001626 CFTR ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.967109 View
ENSG00000001626 CFTR ENSG00000077721 UBE2A H. sapiens SSL Slorth 0.966978 View
ENSG00000001626 CFTR ENSG00000135090 TAOK3 H. sapiens SDL Slorth 0.966942 View
ENSG00000001626 CFTR ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.96691 View
ENSG00000001626 CFTR ENSG00000074219 TEAD2 H. sapiens SDL Slorth 0.966781 View
ENSG00000001626 CFTR ENSG00000114423 CBLB H. sapiens SSL Slorth 0.966646 View
ENSG00000001626 CFTR ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.966403 View
ENSG00000001626 CFTR ENSG00000105401 CDC37 H. sapiens SSL Slorth 0.966385 View
ENSG00000001626 CFTR ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.966314 View
ENSG00000001626 CFTR ENSG00000102882 MAPK3 H. sapiens SSL Slorth 0.966302 View
ENSG00000001626 CFTR ENSG00000065978 YBX1 H. sapiens SSL Slorth 0.966238 View
ENSG00000001626 CFTR ENSG00000103126 AXIN1 H. sapiens SSL Slorth 0.966117 View
ENSG00000001626 CFTR ENSG00000124784 RIOK1 H. sapiens SDL Slorth 0.966039 View
ENSG00000001626 CFTR ENSG00000087274 ADD1 H. sapiens SDL Slorth 0.966002 View
ENSG00000001626 CFTR ENSG00000023318 ERP44 H. sapiens SDL Slorth 0.965956 View
ENSG00000001626 CFTR ENSG00000186868 MAPT H. sapiens SSL Slorth 0.965892 View
ENSG00000001626 CFTR ENSG00000065029 ZNF76 H. sapiens SDL Slorth 0.965838 View
ENSG00000001626 CFTR ENSG00000117625 RCOR3 H. sapiens SDL Slorth 0.965789 View
ENSG00000001626 CFTR ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.965737 View
ENSG00000001626 CFTR ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.96555 View
ENSG00000001626 CFTR ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.965414 View
ENSG00000001626 CFTR ENSG00000141968 VAV1 H. sapiens SSL Slorth 0.96519 View