CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000105290 APLP1 H. sapiens SDL Slorth 0.973648 View
ENSG00000001626 CFTR ENSG00000111276 CDKN1B H. sapiens SSL Slorth 0.973583 View
ENSG00000001626 CFTR ENSG00000100503 NIN H. sapiens SDL Slorth 0.973535 View
ENSG00000001626 CFTR ENSG00000067082 KLF6 H. sapiens SDL Slorth 0.973505 View
ENSG00000001626 CFTR ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.973505 View
ENSG00000001626 CFTR ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.973505 View
ENSG00000001626 CFTR ENSG00000160224 AIRE H. sapiens SDL Slorth 0.973344 View
ENSG00000001626 CFTR ENSG00000088367 EPB41L1 H. sapiens SDL Slorth 0.973321 View
ENSG00000001626 CFTR ENSG00000145604 SKP2 H. sapiens SSL Slorth 0.973144 View
ENSG00000001626 CFTR ENSG00000116017 ARID3A H. sapiens SDL Slorth 0.973077 View
ENSG00000001626 CFTR ENSG00000143344 RGL1 H. sapiens SDL Slorth 0.973065 View
ENSG00000001626 CFTR ENSG00000129559 NEDD8 H. sapiens SSL Slorth 0.973011 View
ENSG00000001626 CFTR ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.973006 View
ENSG00000001626 CFTR ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.972844 View
ENSG00000001626 CFTR ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.972612 View
ENSG00000001626 CFTR ENSG00000131759 RARA H. sapiens SSL Slorth 0.972423 View
ENSG00000001626 CFTR ENSG00000143033 MTF2 H. sapiens SDL Slorth 0.972413 View
ENSG00000001626 CFTR ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.972188 View
ENSG00000001626 CFTR ENSG00000138756 BMP2K H. sapiens SDL Slorth 0.971411 View
ENSG00000001626 CFTR ENSG00000100906 NFKBIA H. sapiens SSL Slorth 0.971398 View
ENSG00000001626 CFTR ENSG00000109320 NFKB1 H. sapiens SSL Slorth 0.971317 View
ENSG00000001626 CFTR ENSG00000102010 BMX H. sapiens SDL Slorth 0.9713 View
ENSG00000001626 CFTR ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.971287 View
ENSG00000001626 CFTR ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.971176 View
ENSG00000001626 CFTR ENSG00000101213 PTK6 H. sapiens SDL Slorth 0.971036 View
ENSG00000001626 CFTR ENSG00000124782 RREB1 H. sapiens SDL Slorth 0.97087 View
ENSG00000001626 CFTR ENSG00000007264 MATK H. sapiens SDL Slorth 0.970825 View
ENSG00000001626 CFTR ENSG00000115355 CCDC88A H. sapiens SDL Slorth 0.970706 View
ENSG00000001626 CFTR ENSG00000028277 POU2F2 H. sapiens SDL Slorth 0.970486 View
ENSG00000001626 CFTR ENSG00000177889 UBE2N H. sapiens SSL Slorth 0.970414 View
ENSG00000001626 CFTR ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.970211 View
ENSG00000001626 CFTR ENSG00000101349 PAK5 H. sapiens SDL Slorth 0.970119 View
ENSG00000001626 CFTR ENSG00000100852 ARHGAP5 H. sapiens SDL Slorth 0.970033 View
ENSG00000001626 CFTR ENSG00000119048 UBE2B H. sapiens SSL Slorth 0.969782 View
ENSG00000001626 CFTR ENSG00000112144 ICK H. sapiens SDL Slorth 0.969727 View
ENSG00000001626 CFTR ENSG00000108924 HLF H. sapiens SDL Slorth 0.969685 View
ENSG00000001626 CFTR ENSG00000100644 HIF1A H. sapiens SSL Slorth 0.968985 View
ENSG00000001626 CFTR ENSG00000070159 PTPN3 H. sapiens SDL Slorth 0.968777 View
ENSG00000001626 CFTR ENSG00000141543 EIF4A3 H. sapiens SSL Slorth 0.968704 View
ENSG00000001626 CFTR ENSG00000213341 CHUK H. sapiens SSL Slorth 0.968692 View