CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000081307 UBA5 H. sapiens SSL Slorth 0.755725 View
ENSG00000001626 CFTR ENSG00000090621 PABPC4 H. sapiens SSL Slorth 0.755665 View
ENSG00000001626 CFTR ENSG00000170348 TMED10 H. sapiens SSL Slorth 0.755436 View
ENSG00000001626 CFTR ENSG00000115041 KCNIP3 H. sapiens SSL Slorth 0.755413 View
ENSG00000001626 CFTR ENSG00000125257 ABCC4 H. sapiens SSL Slorth 0.755043 View
ENSG00000001626 CFTR ENSG00000082781 ITGB5 H. sapiens SSL Slorth 0.754781 View
ENSG00000001626 CFTR ENSG00000162736 NCSTN H. sapiens SSL Slorth 0.75478 View
ENSG00000001626 CFTR ENSG00000239672 NME1 H. sapiens SSL Slorth 0.754772 View
ENSG00000001626 CFTR ENSG00000111199 TRPV4 H. sapiens SSL Slorth 0.75436 View
ENSG00000001626 CFTR ENSG00000205302 SNX2 H. sapiens SSL Slorth 0.754307 View
ENSG00000001626 CFTR ENSG00000187266 EPOR H. sapiens SSL Slorth 0.754214 View
ENSG00000001626 CFTR ENSG00000198612 COPS8 H. sapiens SSL Slorth 0.75412 View
ENSG00000001626 CFTR ENSG00000181929 PRKAG1 H. sapiens SSL Slorth 0.754054 View
ENSG00000001626 CFTR ENSG00000173207 CKS1B H. sapiens SSL Slorth 0.754045 View
ENSG00000001626 CFTR ENSG00000108312 UBTF H. sapiens SSL Slorth 0.753941 View
ENSG00000001626 CFTR ENSG00000101162 TUBB1 H. sapiens SSL Slorth 0.75386 View
ENSG00000001626 CFTR ENSG00000118680 MYL12B H. sapiens SSL Slorth 0.753706 View
ENSG00000001626 CFTR ENSG00000178921 PFAS H. sapiens SSL Slorth 0.753152 View
ENSG00000001626 CFTR ENSG00000145349 CAMK2D H. sapiens SSL Slorth 0.752947 View
ENSG00000001626 CFTR ENSG00000109339 MAPK10 H. sapiens SSL Slorth 0.752406 View
ENSG00000001626 CFTR ENSG00000007944 MYLIP H. sapiens SSL Slorth 0.75239 View
ENSG00000001626 CFTR ENSG00000100591 AHSA1 H. sapiens SSL Slorth 0.752276 View
ENSG00000001626 CFTR ENSG00000115816 CEBPZ H. sapiens SSL Slorth 0.752105 View
ENSG00000001626 CFTR ENSG00000119487 MAPKAP1 H. sapiens SSL Slorth 0.751939 View
ENSG00000001626 CFTR ENSG00000127824 TUBA4A H. sapiens SSL Slorth 0.751689 View
ENSG00000001626 CFTR ENSG00000100284 TOM1 H. sapiens SSL Slorth 0.751513 View
ENSG00000001626 CFTR ENSG00000167460 TPM4 H. sapiens SSL Slorth 0.751465 View
ENSG00000001626 CFTR ENSG00000143549 TPM3 H. sapiens SSL Slorth 0.751465 View
ENSG00000001626 CFTR ENSG00000056097 ZFR H. sapiens SSL Slorth 0.751082 View
ENSG00000001626 CFTR ENSG00000100911 PSME2 H. sapiens SSL Slorth 0.751022 View
ENSG00000001626 CFTR ENSG00000115685 PPP1R7 H. sapiens SSL Slorth 0.750996 View
ENSG00000001626 CFTR ENSG00000152056 AP1S3 H. sapiens SSL Slorth 0.750745 View
ENSG00000001626 CFTR ENSG00000110171 TRIM3 H. sapiens SSL Slorth 0.750457 View
ENSG00000001626 CFTR ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.750427 View
ENSG00000001626 CFTR ENSG00000136152 COG3 H. sapiens SSL Slorth 0.750421 View