CFTR

ENSG00000001626 - H. sapiens

Pathways

Go term Description
GO:0005254 chloride channel activity
GO:0005260 intracellular ATPase-gated chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0017081 chloride channel regulator activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0043225 ATPase-coupled anion transmembrane transporter activity

Drugs

Drug name Description
CROFELEMER Cystic fibrosis transmembrane conductance regulator inhibitor
IVACAFTOR Cystic fibrosis transmembrane conductance regulator positive modulator
LUMACAFTOR Cystic fibrosis transmembrane conductance regulator stabiliser

Diseases

No diseases in record

Orthologs

Gene Organism
BPT1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000127564 PKMYT1 H. sapiens SSL Slorth 0.787448 View
ENSG00000001626 CFTR ENSG00000145147 SLIT2 H. sapiens SSL Slorth 0.787202 View
ENSG00000001626 CFTR ENSG00000092621 PHGDH H. sapiens SSL Slorth 0.786952 View
ENSG00000001626 CFTR ENSG00000254505 CHMP4A H. sapiens SSL Slorth 0.786756 View
ENSG00000001626 CFTR ENSG00000100804 PSMB5 H. sapiens SSL Slorth 0.786416 View
ENSG00000001626 CFTR ENSG00000107186 MPDZ H. sapiens SSL Slorth 0.786394 View
ENSG00000001626 CFTR ENSG00000186153 WWOX H. sapiens SSL Slorth 0.786391 View
ENSG00000001626 CFTR ENSG00000108840 HDAC5 H. sapiens SSL Slorth 0.786368 View
ENSG00000001626 CFTR ENSG00000163399 ATP1A1 H. sapiens SSL Slorth 0.786276 View
ENSG00000001626 CFTR ENSG00000187741 FANCA H. sapiens SSL Slorth 0.786207 View
ENSG00000001626 CFTR ENSG00000055332 EIF2AK2 H. sapiens SSL Slorth 0.786078 View
ENSG00000001626 CFTR ENSG00000019995 ZRANB1 H. sapiens SSL Slorth 0.785708 View
ENSG00000001626 CFTR ENSG00000143878 RHOB H. sapiens SSL Slorth 0.785446 View
ENSG00000001626 CFTR ENSG00000125814 NAPB H. sapiens SSL Slorth 0.785335 View
ENSG00000001626 CFTR ENSG00000115085 ZAP70 H. sapiens SSL Slorth 0.784984 View
ENSG00000001626 CFTR ENSG00000005844 ITGAL H. sapiens SSL Slorth 0.784655 View
ENSG00000001626 CFTR ENSG00000128908 INO80 H. sapiens SSL Slorth 0.784511 View
ENSG00000001626 CFTR ENSG00000127314 RAP1B H. sapiens SSL Slorth 0.784394 View
ENSG00000001626 CFTR ENSG00000122565 CBX3 H. sapiens SSL Slorth 0.784224 View
ENSG00000001626 CFTR ENSG00000205220 PSMB10 H. sapiens SSL Slorth 0.784159 View
ENSG00000001626 CFTR ENSG00000124193 SRSF6 H. sapiens SSL Slorth 0.783987 View
ENSG00000001626 CFTR ENSG00000126858 RHOT1 H. sapiens SSL Slorth 0.783856 View
ENSG00000001626 CFTR ENSG00000081189 MEF2C H. sapiens SSL Slorth 0.783767 View
ENSG00000001626 CFTR ENSG00000007312 CD79B H. sapiens SSL Slorth 0.783448 View
ENSG00000001626 CFTR ENSG00000196235 SUPT5H H. sapiens SSL Slorth 0.783376 View
ENSG00000001626 CFTR ENSG00000185344 ATP6V0A2 H. sapiens SSL Slorth 0.783324 View
ENSG00000001626 CFTR ENSG00000168118 RAB4A H. sapiens SSL Slorth 0.783314 View
ENSG00000001626 CFTR ENSG00000151348 EXT2 H. sapiens SSL Slorth 0.783301 View
ENSG00000001626 CFTR ENSG00000114416 FXR1 H. sapiens SSL Slorth 0.783301 View
ENSG00000001626 CFTR ENSG00000149269 PAK1 H. sapiens SSL Slorth 0.783218 View
ENSG00000001626 CFTR ENSG00000112118 MCM3 H. sapiens SSL Slorth 0.783057 View
ENSG00000001626 CFTR ENSG00000083642 PDS5B H. sapiens SSL Slorth 0.782822 View
ENSG00000001626 CFTR ENSG00000116266 STXBP3 H. sapiens SSL Slorth 0.782245 View
ENSG00000001626 CFTR ENSG00000075711 DLG1 H. sapiens SSL Slorth 0.782213 View
ENSG00000001626 CFTR ENSG00000007168 PAFAH1B1 H. sapiens SSL Slorth 0.782056 View
ENSG00000001626 CFTR ENSG00000184009 ACTG1 H. sapiens SSL Slorth 0.781998 View
ENSG00000001626 CFTR ENSG00000132356 PRKAA1 H. sapiens SSL Slorth 0.781653 View
ENSG00000001626 CFTR ENSG00000100749 VRK1 H. sapiens SSL Slorth 0.781519 View
ENSG00000001626 CFTR ENSG00000164690 SHH H. sapiens SSL Slorth 0.781511 View
ENSG00000001626 CFTR ENSG00000121691 CAT H. sapiens SSL Slorth 0.781212 View