DNA2

ENSG00000138346 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base
GO:0017108 5'-flap endonuclease activity
GO:0043139 5'-3' DNA helicase activity
GO:0043142 single-stranded DNA-dependent ATPase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003824 catalytic activity
GO:0004003 ATP-dependent DNA helicase activity
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0051536 iron-sulfur cluster binding
GO:0003682 chromatin binding
GO:1990601 5' overhang single-stranded DNA endodeoxyribonuclease activity
GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
DNA2 S. cerevisiae
dna-2 C. elegans
CG2990 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000112249 ASCC3 ENSG00000138346 DNA2 H. sapiens SSL BioGRID 1.0 View
ENSG00000133703 KRAS ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.977368 View
ENSG00000109670 FBXW7 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.975833 View
ENSG00000116030 SUMO1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.971621 View
ENSG00000101266 CSNK2A1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.970678 View
ENSG00000005339 CREBBP ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.969266 View
ENSG00000136997 MYC ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.96881 View
ENSG00000103275 UBE2I ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.967706 View
ENSG00000135486 HNRNPA1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.966479 View
ENSG00000123374 CDK2 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.965023 View
ENSG00000134086 VHL ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.964732 View
ENSG00000121022 COPS5 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.964587 View
ENSG00000100030 MAPK1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.963192 View
ENSG00000097007 ABL1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.960727 View
ENSG00000012048 BRCA1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.958863 View
ENSG00000096717 SIRT1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.957064 View
ENSG00000101146 RAE1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.955727 View
ENSG00000124762 CDKN1A ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.955367 View
ENSG00000132383 RPA1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.954676 View
ENSG00000097046 CDC7 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.95421 View
ENSG00000109971 HSPA8 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.952857 View
ENSG00000112062 MAPK14 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.952212 View
ENSG00000114166 KAT2B ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.951042 View
ENSG00000101412 E2F1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.949276 View
ENSG00000113558 SKP1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.949139 View
ENSG00000117399 CDC20 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.948295 View
ENSG00000112592 TBP ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.948235 View
ENSG00000073111 MCM2 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.947852 View
ENSG00000131759 RARA ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.946409 View
ENSG00000004700 RECQL ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.946406 View
ENSG00000111276 CDKN1B ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.944055 View
ENSG00000101868 POLA1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.943559 View
ENSG00000004897 CDC27 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.942874 View
ENSG00000094804 CDC6 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.942279 View
ENSG00000091831 ESR1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.940612 View
ENSG00000130726 TRIM28 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.940295 View
ENSG00000055130 CUL1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.940004 View
ENSG00000110092 CCND1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.939167 View
ENSG00000113575 PPP2CA ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.938772 View
ENSG00000108443 RPS6KB1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.938128 View