MAPK1 - DNA2

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
MAPK1 ENSG00000100030 CLL
ovarian mixed germ cell tumour
cervical carcinoma

No drugs in record

phosphotyrosine residue binding
DNA binding
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
transcription factor binding
RNA polymerase II carboxy-terminal domain kinase activity
kinase activity
phosphatase binding
mitogen-activated protein kinase kinase kinase binding
identical protein binding
FUS3 (S. cerevisiae)
KSS1 (S. cerevisiae)
mpk-1 (C. elegans)
rl (D. melanogaster)
DNA2 ENSG00000138346

No diseases in record

No drugs in record

DNA binding
DNA helicase activity
helicase activity
nuclease activity
protein binding
ATP binding
ATPase activity
site-specific endodeoxyribonuclease activity, specific for altered base
5'-flap endonuclease activity
5'-3' DNA helicase activity
single-stranded DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding
catalytic activity
ATP-dependent DNA helicase activity
single-stranded DNA endodeoxyribonuclease activity
nucleotide binding
hydrolase activity
iron-sulfur cluster binding
chromatin binding
5' overhang single-stranded DNA endodeoxyribonuclease activity
single-stranded DNA 5'-3' exodeoxyribonuclease activity
DNA2 (S. cerevisiae)
dna-2 (C. elegans)
CG2990 (D. melanogaster)