TBP - DNA2

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TBP	ENSG00000112592	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase III transcription factor activity, sequence-specific DNA binding RNA polymerase II repressing transcription factor binding protein binding transcription factor binding enzyme binding transcription regulatory region DNA binding repressing transcription factor binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly TFIIA-class transcription factor binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly core promoter binding chromatin binding	SPT15 (S. cerevisiae) tbp-1 (C. elegans) Tbp (D. melanogaster)
DNA2	ENSG00000138346	No diseases in record	No drugs in record	DNA binding DNA helicase activity helicase activity nuclease activity protein binding ATP binding ATPase activity site-specific endodeoxyribonuclease activity, specific for altered base 5'-flap endonuclease activity 5'-3' DNA helicase activity single-stranded DNA-dependent ATPase activity metal ion binding 4 iron, 4 sulfur cluster binding catalytic activity ATP-dependent DNA helicase activity single-stranded DNA endodeoxyribonuclease activity nucleotide binding hydrolase activity iron-sulfur cluster binding chromatin binding 5' overhang single-stranded DNA endodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity	DNA2 (S. cerevisiae) dna-2 (C. elegans) CG2990 (D. melanogaster)