ABL1 - DNA2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
DNA2	ENSG00000138346	No diseases in record	No drugs in record	DNA binding DNA helicase activity helicase activity nuclease activity protein binding ATP binding ATPase activity site-specific endodeoxyribonuclease activity, specific for altered base 5'-flap endonuclease activity 5'-3' DNA helicase activity single-stranded DNA-dependent ATPase activity metal ion binding 4 iron, 4 sulfur cluster binding catalytic activity ATP-dependent DNA helicase activity single-stranded DNA endodeoxyribonuclease activity nucleotide binding hydrolase activity iron-sulfur cluster binding chromatin binding 5' overhang single-stranded DNA endodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity	DNA2 (S. cerevisiae) dna-2 (C. elegans) CG2990 (D. melanogaster)